Determinants of the quality of life of patients with diabetes under intensified insulin therapy.

Rose, Marisa; Burkert, U; Scholler, G; Schirop, Th.; Danzer, Gerhard; Klapp, BF

doi:10.2337/diacare.21.11.1876

Cited by 56 publications

(45 citation statements)

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“…Overall HRQoL in diabetes is affected by various domains of functioning and well-being, implying the need for a multidimensional measurement approach. 42 However, it is usually the combined effect of macrovascular and microvascular complications, comorbid conditions, and background demographic, clinical and treatment satisfaction variables which degrade HRQoL and not diabetes per se. 43 The results of the known-groups comparisons performed here conform to the literature 1,[12][13][14][15]17,[27][28][38][39][40][41] in terms of the score differences and the direction of these differences.…”

Section: Discussionmentioning

confidence: 99%

Validity and reliability of the Greek version of the Diabetic Foot Ulcer Scale - Short Form (DFS-SF)

Kontodimopoulos

Veniou

Tentolouris

et al. 2016

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ObJECTIvE: Diabetic foot ulcer is a critical and costly complication of diabetes mellitus. The aim of this study was to assess the psychometric properties of the greek version of the diabetic foot ulcer scale -short form (DFS-SF). DESIgN: a sample of patients with diabetic foot ulcer (N=110) was surveyed with the DFS-SF and various demographic and disease-related questions. The validated greek SF-36 instrument was used as a "gold standard" for health-related quality of life comparisons. hypothesized scale structure, internal consistency reliability (Cronbach's alpha) and various forms of construct validity (convergent, discriminative, concurrent and known -groups) were assessed. RESUlTS: multitrait scaling confirmed the scale structure of the DFS-SF, with 32 excellent item convergence (100%) and good discrimination (84.1%) rates. Cronbach's alpha was >0.70 for all scales. Spearman's correlations between similar DFS-SF and SF-36 scales ranged between 0.39-0.79 (p<0.001). Expected interscale correlations and knowngroups comparisons supported construct validity. CONClUSIONS: The observed psychometric properties of the greek DFS-SF imply suitability for assessing health-related quality of life in patients with diabetic foot ulcer. Future studies should focus on generalizability of the results, as well as on specific issues such as longitudinal validity and responsiveness.

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Section: Discussionmentioning

confidence: 99%

Validity and reliability of the Greek version of the Diabetic Foot Ulcer Scale - Short Form (DFS-SF)

Kontodimopoulos

Veniou

Tentolouris

et al. 2016

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“…We find that depressed subjects generally have a poorer quality of life, independent of the physical illnesses from which they might suffer (9 -12). This also applies to patients with diabetes whose personality dispositions appear to be more significant for the quality of life than, for instance, the presence of secondary illnesses (8,13,14). The patient's psychological disposition is, in turn, closely connected to cognitive and emotional aspects of his/her illness-coping strategies, which indirectly affect their healthseeking behavior (15).…”

Section: Quality Of Lifementioning

confidence: 99%

The Network of Psychological Variables in Patients With Diabetes and Their Importance for Quality of Life and Metabolic Control

et al. 2002

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OBJECTIVE -The primary goals in treating patients with diabetes are maintaining blood glucose levels as close to normal as possible and making a relatively normal quality of life achievable. Both of these goals are influenced by a multitude of somatic and psychological factors that should be seen as building a complex network. We examined whether a mathematical model can be construed that can depict the relative significance of each factor for achieving these treatment goals. RESEARCH DESIGN AND METHODS

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“…Earlier studies have suggested that obesity (BMI >30) and depression may also be significant predictors of health-related quality of life and patient utility in type 2 diabetes [7,8,11,12]. Initially, we chose not to include these among our predictor variables: obesity is not necessarily a morbid condition per se, and in the context of type 2 diabetes may be both a cause and a consequence of developing metabolic dysfunction; depression is also not recognised as a primary complication of diabetes, and may be more properly seen as a secondary outcome consequent on other complications.…”

Section: General Principles and Assumptionsmentioning

confidence: 99%

Modelling EuroQol health‐related utility values for diabetic complications from CODE‐2 data

2004

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Recent research has employed different analytical techniques to estimate the impact of the various long-term complications of type 2 diabetes on health-related utility and health status. However, limited patient numbers or lack of variety of patient experience has limited their power to discriminate between separate complications and grades of severity. In this study alternative statistical model forms were compared to investigate the influence of various factors on self-assessed health status and calculated utility scores, including the presence and severity of complications, and type of diabetes therapy. Responses to the EuroQol EQ-5D questionnaire from 4641 patients with type 2 diabetes in 5 European countries were analysed. Simple multiple regression analysis was used to model both visual analogue scale (VAS) scores and time trade-off index scores (TTO). Also, two complex models were developed for TTO analysis using a structure suggested by the EuroQol calculation algorithm. Both VAS and TTO models achieved greater explanatory power than in earlier studies. Relative weightings for individual complications differed between VAS and TTO scales, reflecting the strong influence of loss of mobility and severe pain in the EuroQol algorithm. Insulin-based therapy was uniformly associated with a detrimental effect equivalent to an additional moderate complication. Evidence was found that TTO values are not responsive in cases where 3 or more multiple complications are present, and therefore may underestimate utility loss for patients most adversely affected by complex chronic diseases like diabetes.

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Determinants of the quality of life of patients with diabetes under intensified insulin therapy.

Cited by 56 publications

References 0 publications

Validity and reliability of the Greek version of the Diabetic Foot Ulcer Scale - Short Form (DFS-SF)

Validity and reliability of the Greek version of the Diabetic Foot Ulcer Scale - Short Form (DFS-SF)

The Network of Psychological Variables in Patients With Diabetes and Their Importance for Quality of Life and Metabolic Control

Modelling EuroQol health‐related utility values for diabetic complications from CODE‐2 data

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