2002
DOI: 10.1016/s0360-3016(02)02881-x
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Determination and delineation of nodal target volumes for head-and-neck cancer based on patterns of failure in patients receiving definitive and postoperative IMRT

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Cited by 225 publications
(130 citation statements)
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“…This finding motivates reducing the doses to the salivary glands to as low levels as possible. Data on dose response in the parotid glands are accumulating [10,[52][53][54][55]. The common finding with all these data is that a relationship seems to exist between the mean doses to the glands and their residual salivary output.…”
Section: Less Normal Tissue Morbidity With Imrtmentioning
confidence: 94%
See 1 more Smart Citation
“…This finding motivates reducing the doses to the salivary glands to as low levels as possible. Data on dose response in the parotid glands are accumulating [10,[52][53][54][55]. The common finding with all these data is that a relationship seems to exist between the mean doses to the glands and their residual salivary output.…”
Section: Less Normal Tissue Morbidity With Imrtmentioning
confidence: 94%
“…Over the past few years, several authors have made recommendations for a more precise selection of the clinical target volume (CTV) for both primary tumors and neck nodes [10,13,14]. It is beyond the scope of this review article to discuss these recommendations at length.…”
Section: Challenge Of Selection and Delineation Of The Target Volumesmentioning
confidence: 99%
“…The optimization tools require an accurate calculation of delivered dose associated with each field and field‐intensity pattern. In some treatment sites (e.g., head and neck), ( 3 5 ) the desired target volumes and/or normal tissue volumes encroach into surface buildup dose regions of the patient where the radiation dose from entering photon beams has not reached electronic equilibrium. Buildup doses near the surface are subject to variations in scattered radiation in the form of electrons and photons streaming from the treatment head and thus are dependent of the treatment machine configuration.…”
Section: Introductionmentioning
confidence: 99%
“…Recent reports have indicated that the technical and dosimetric superiority of 3D-CRT and IMRT over 2D-RT can translate into clinical benefits, such as reduced normal tissue toxicity (eg, parotid gland sparing), improved local control, and patient survival. [3][4][5][6][7][8][9][10][11][12] In addition to such conventional parameters as survival, local control, and complication rates, the subjective well-being of patients who are cured of their disease is equally important and increasingly is emphasized in chronic health care, especially in the field of cancer treatment. Quality of life (QOL) indicates an individual's conception of well-being.…”
mentioning
confidence: 99%