Lean premixed combustion chambers fuelled by natural gas and used in modern gas turbines for power generation are often affected by combustion instabilities generated by mutual interactions between pressure fluctuations and heat oscillations produced by the flame. Due to propagation and reflection of the acoustic waves in the combustion chamber, very strong pressure oscillations are generated and the chamber may be damaged. This phenomenon is generally referred as thermoacoustic instability, or humming, owing to the cited coupling mechanism of pressure waves and heat release fluctuations.Over the years, several different approaches have been developed in order to model this phenomenon and to define a method able to predict the onset of thermoacoustic instabilities. In order to validate analytical and numerical thermoacoustic models, experimental data are required. In this context, an experimental test rig is designed and operated in order to characterize the propensity of the burner to determine thermoacoustic instabilities.In this paper, a method able to predict the onset of thermoacoustic instabilities is examined and applied to a test rig in order to validate the proposed methodology. The experimental test is designed to evaluate the propensity to thermoacoustic instabilities of full scale Ansaldo Energia burners used in gas turbine systems for production of energy.The experimental work is conducted in collaboration with Ansaldo Energia and CCA (Centro Combustione e Ambiente) at the Ansaldo Caldaie facility in Gioia del Colle (Italy).Under the hypotheses of low Mach number approximation and linear behaviour of the acoustic waves, the heat release fluctuations are introduced in the acoustic equations as source term. In the frequency domain, a complex eigenvalue problem is solved. It allow us to identify the frequencies of thermoacoustic instabilities and the growth rate of the pressure oscillations.The Burner Transfer Matrix (BTM) approach is used to characterize the influence of the burner characteristics. Furthermore, the influence of different operative conditions is examined considering temperature gradients along the combustion chamber.