Determination of (2E)-10-hydroxydec-2-enoic acid in Croatian royal jelly by high-performance liquid chromatography

Flanjak, Ivana; Jakovljević, Martina; Kenjerić, Daniela; Stokanović, Milica Cvijetić; Primorac, Ljiljana; Rajs, Blanka Bilić

doi:10.17508/cjfst.2017.9.2.10

Cited by 8 publications

(5 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The question is whether 10-HDA reaches such inhibitory concentrations in the larval midguts. The contents of 10-HDA have been analyzed in numerous RJ samples of various geographic and hive origins and were found to vary between 0.75% and 6.4% [63,64,65,66,67,68,69,70,71,72]. These percentages correspond to 7.5–64 μg of 10-HDA per 1 mg of RJ.…”

Section: Discussionmentioning

confidence: 99%

10-HDA, A Major Fatty Acid of Royal Jelly, Exhibits pH Dependent Growth-Inhibitory Activity Against Different Strains of Paenibacillus larvae

et al. 2018

View full text Add to dashboard Cite

Paenibacillus larvae (P. larvae) is a bacterial pathogen causing American foulbrood (AFB), the most serious disease of honeybee larvae. The food of young larvae could play an important role in the resistance of larvae against AFB. It contains antibacterial substances produced by honeybees that may inhibit the propagation of the pathogen in larval midguts. In this study, we identified and investigated the antibacterial effects of one of these substances, trans-10-hydroxy-2-decenoic acid (10-HDA), against P. larvae strains including all Enterobacterial Repetitive Intergenic Consensus (ERIC) genotypes. Its inhibitory activities were studied by determining the minimum inhibitory concentrations (MICs). It was found that 10-HDA efficacy increases substantially with decreasing pH; up to 12-fold differences in efficacy were observed between pH = 5.5 and pH = 7.2. P. larvae strains showed different susceptibility to 10-HDA; up to 2.97-fold differences existed among various strains with environmentally important ERIC I and ERIC II genotypes. Germinating spores of the pathogen were generally more susceptible to 10-HDA than vegetative cells. Our findings suggest that 10-HDA could play significant role in conferring antipathogenic activity to larval food in the midguts of young larvae and contribute to the resistance of individual larvae to P. larvae.

show abstract

Section: Discussionmentioning

confidence: 99%

10-HDA, A Major Fatty Acid of Royal Jelly, Exhibits pH Dependent Growth-Inhibitory Activity Against Different Strains of Paenibacillus larvae

et al. 2018

View full text Add to dashboard Cite

show abstract

“…Greek RJ had higher maximal value for 10-HDA content from 0.8 % to 6.5 % (Kanelis et al, 2015). The content of 10-HDA in Croatian RJ varied from 1.56% up to 3.78% (Flanjak et al, 2017).…”

Section: Resultsmentioning

confidence: 98%

Determination of Trans-10-Hydroxy-2-Decenoic Acid in Royal Jelly by High Performance Liquid Chromatography after Different Bee Feeding

Balkanska¹

2018

Int.J.Curr.Microbiol.App.Sci

View full text Add to dashboard Cite

“…This indicated that all the samples were able to meet the quality criteria set by the International Organization of Standardization and the International Honey Commission. According to these institutions, fresh and genuine RJ should contain a minimum 1.4% of 10-HDA ( Flanjak et al., 2017 ). Meanwhile, the PCA enabled for a comprehensive approach to reveal the distinct chemical differences among the four RJ samples, with the compounds responsible for these differences also identified.…”

Section: Resultsmentioning

confidence: 99%

Metabolome analysis and chemical profiling of Indonesian royal jellies as the raw material for cosmetic and bio-supplement products

Sari

Mahira

Patel³

et al. 2021

Heliyon

View full text Add to dashboard Cite

Royal jellies (RJs) possess moisturizing, emulsifying, and stabilizing properties, and several pharmacological activities have also been found to be present, which make them an ideal component for cosmetic and skin care products. However, despite the abundant efficacies, there is a lack of studies that explore the chemical composition of RJ using metabolome analysis. Furthermore, an evaluation of the chemical composition of Indonesian RJs collected from different regions has yet to be carried out. Therefore, the main objective of this study was to identify any differences in the chemical composition of such RJs. Chemical profiling was also carried out to enable more targeted utilization based on the actual compositions. Chemical profiling is also important given the rich Indonesian biodiversity and the high dependence of the RJ compositions on the botanical source. In this research, ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry was used as part of an untargeted metabolomics approach. From the chemical profiling, >30 compounds were identified across four RJ samples. The major constituents of the samples were found to be oligosaccharides, fatty acids, and adenosine monophosphate derivatives. Meanwhile, sucrose and planteose were found to be highest in the samples from Banjarnegara and Kediri, whereas dimethyloctanoic acid was found to be unique to the sample from Banjarnegara. It was also discovered that the RJs from Demak and Tuban contained more organic fatty acids and oligosaccharides than the other samples. Although the sample from Demak demonstrated good potential for use in the cosmetic, skin care, and bio-supplement industries, the higher abundance of fatty acids and oligosaccharides in the sample from Tuban indicated that it is perhaps the most suitable RJ for use in this field.

show abstract

Determination of (2E)-10-hydroxydec-2-enoic acid in Croatian royal jelly by high-performance liquid chromatography

Abstract: Indexing p. 1  Editorial Bord p. 1  Guide for Authors p. 3  Manuscript preparation p. 5

Cited by 8 publications

References 0 publications

10-HDA, A Major Fatty Acid of Royal Jelly, Exhibits pH Dependent Growth-Inhibitory Activity Against Different Strains of Paenibacillus larvae

10-HDA, A Major Fatty Acid of Royal Jelly, Exhibits pH Dependent Growth-Inhibitory Activity Against Different Strains of Paenibacillus larvae

Determination of Trans-10-Hydroxy-2-Decenoic Acid in Royal Jelly by High Performance Liquid Chromatography after Different Bee Feeding

Metabolome analysis and chemical profiling of Indonesian royal jellies as the raw material for cosmetic and bio-supplement products

Contact Info

Product

Resources

About