Determination of 4-aminophenol in a pharmaceutical formulation using surface enhanced Raman scattering: From development to method validation

Bleye, Charlotte De; Dumont, Elodie; Rozet, Eric; Chavez, Pierre-François; Netchacovitch, Lauranne; Piel, Géraldine; Hubert, Ph.; Ziemons, Eric

doi:10.1016/j.talanta.2013.07.084

Cited by 56 publications

(23 citation statements)

References 54 publications

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“…4‐Aminophenol (4‐AP) is a carcinogenic and highly toxic chemical, which is extensively used in pharmaceutical industries for the manufacture of paracetamol and clofibrates . Photographic, cosmetics and many other industries are also frequently using 4‐AP as industrial, raw and processed material.…”

Section: Introductionmentioning

confidence: 99%

Electrocatalytic Oxidation of 4‐Aminophenol Molecules at the Surface of an FeS₂/Carbon Nanotube Modified Glassy Carbon Electrode in Aqueous Medium

et al. 2019

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FeS2/carbon nanotube (CNT) nanocomposites were synthesized and immobilized on the surface of a glassy carbon electrode (GCE) in order to investigate the electrocatalytic conversion of 4‐aminophenol (4‐AP) into p‐quinone in an aqueous medium. The reformed electronic properties (in terms of lowering of band‐gap energy and charge‐transfer resistance), as well as improved surface area, result in an enhanced redox reaction of 4‐AP in the presence of FeS2‐CNT NCs compared to that with FeS2 alone. The 4‐AP molecules undergo coupled two‐proton and two‐electron transfer quasi‐reversible redox reactions with a symmetry factor of 0.55 and standard rate constant (k°) of 0.8 cm s−1. Here, quinone imine is generated as an intermediate which is later converted into quinone in an irreversible hydrolysis reaction. The best catalytic performance can be obtained at the pH value of 7.0.

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Section: Introductionmentioning

confidence: 99%

Electrocatalytic Oxidation of 4‐Aminophenol Molecules at the Surface of an FeS₂/Carbon Nanotube Modified Glassy Carbon Electrode in Aqueous Medium

et al. 2019

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“…21 De Bleye employed a quantified 4-AP in a pharmaceutical formulation containing acetaminophen using surface-enhanced Raman scattering. 22 In addition, Wang et al described a high-performance photo electrochemical sensor for the detection of 4-AP based on an MIP/CdS-GR modified electrode. 23 However, there is increasing demand for simpler analytical devices that can provide rapid results and provide uncomplicated analysis without the demand for a full laboratory setting.…”

Section: Introductionmentioning

confidence: 99%

Preparation of a reduced graphene oxide/poly-l-glutathione nanocomposite for electrochemical detection of 4-aminophenol in orange juice samples

et al. 2015

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A novel electrochemical sensor, 4-aminophenol (4-AP), was generated by electrodeposition of poly-L-glutathione (P-L-GSH) onto reduced graphene oxide (RGO) to form a RGO/P-L-GSH composite matrix on a glassy carbon electrode (RGO/P-L-GSH/GCE). The morphology and structure of RGO/P-L-GSH modified GCE were characterized by scanning electron microscopy (SEM), FT-IR spectroscopy and electrochemical impedance spectroscopy. As an electrochemical sensor, the RGO/P-L-GSH modified GCE composite exhibited strong catalytic activity toward the oxidation of 4-AP by cyclic voltammetry (CV) and chronoamperometry.Furthermore, the electrochemical sensor exhibited an excellent current response for 4-AP over a wide linear range of 0.4 to 200 µM (R 2 = 0.9934) with a lower detection limit (LOD ) of 0.03 µM (S/N = 3), as well as a sensitivity of 27.2 (µA µM -1 cm -2 ) and excellent selectivity, reproducibility and stability. The electrochemical sensor demonstrated good anti-interference ability in the presence of glucose, fructose, paracetamol, ethanol, l-isoluecine, l-histidine, lcysteine, dopamine, l-serine, l-tyrosine, phenylalanine, urea, hydrogen peroxide, K + , Ca 2+ , Na + , F -, SO 4 2-, Cu 2+ , Fe 3+ , Zn 2+ , SO 4 2-, SO 3 2-, Cl -, folic acid and ascorbic acid. The proposed electrochemical method was successfully applied to produce a sensor for the detection of 4-AP in juice and water samples. sensitivity and very low LOD for amperometric determination of 4-AP when compared to most other sensors reported in recent years.The 4-AP sensor was also applied for analysis of juice and water samples, and the results showed it was useful in practical applications. Experimental Section ReagentsThe graphite (powder, <20 lm), L-glutathione, 4-aminophenol, Na 2 HPO 4 and NaH 2 PO 4 , were received from the Sigma ChemicalCompany. In addition a 0.05 M phosphate buffer solution (PBS, pH 7) was used as the supporting electrolyte. Other chemicals were of analytical reagent grade, and all aqueous solutions were prepared with double distilled water for use in the experiments. ApparatusAll the electrochemical measurements were executed on a CHI 405A electrochemical workstation (Shanghai Chenhua Instrument, China).A conventional three-electrode system was used with an RGO/P-L-GSH film modified electrode as the working electrode, a platinum wire as the auxiliary electrode and a saturated Ag/AgCl as the reference electrode. Electrochemical impedance spectroscopy (EIS) was carried out in a frequency range of 0.

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“…Silver nanoparticles were used as SERS substrates because of their ease of synthesis and the possibility of reproducing the AgNps size and shape from batch to batch, as described in a previous publication [29]. The freshly synthesized AgNps were characterized in terms of their size, size distribution and shape using the UVevisible spectrophotometer and the transmission electron microscope.…”

Section: Silver Nanoparticlesmentioning

confidence: 99%

A simple approach for ultrasensitive detection of bisphenols by multiplexed surface-enhanced Raman scattering

Bleye

Dumont

Hubert

et al. 2015

Analytica Chimica Acta

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Determination of 4-aminophenol in a pharmaceutical formulation using surface enhanced Raman scattering: From development to method validation

Cited by 56 publications

References 54 publications

Electrocatalytic Oxidation of 4‐Aminophenol Molecules at the Surface of an FeS₂/Carbon Nanotube Modified Glassy Carbon Electrode in Aqueous Medium

Electrocatalytic Oxidation of 4‐Aminophenol Molecules at the Surface of an FeS₂/Carbon Nanotube Modified Glassy Carbon Electrode in Aqueous Medium

Preparation of a reduced graphene oxide/poly-l-glutathione nanocomposite for electrochemical detection of 4-aminophenol in orange juice samples

A simple approach for ultrasensitive detection of bisphenols by multiplexed surface-enhanced Raman scattering

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Determination of 4-aminophenol in a pharmaceutical formulation using surface enhanced Raman scattering: From development to method validation

Cited by 56 publications

References 54 publications

Electrocatalytic Oxidation of 4‐Aminophenol Molecules at the Surface of an FeS2/Carbon Nanotube Modified Glassy Carbon Electrode in Aqueous Medium

Electrocatalytic Oxidation of 4‐Aminophenol Molecules at the Surface of an FeS2/Carbon Nanotube Modified Glassy Carbon Electrode in Aqueous Medium

Preparation of a reduced graphene oxide/poly-l-glutathione nanocomposite for electrochemical detection of 4-aminophenol in orange juice samples

A simple approach for ultrasensitive detection of bisphenols by multiplexed surface-enhanced Raman scattering

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Product

Resources

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Electrocatalytic Oxidation of 4‐Aminophenol Molecules at the Surface of an FeS₂/Carbon Nanotube Modified Glassy Carbon Electrode in Aqueous Medium

Electrocatalytic Oxidation of 4‐Aminophenol Molecules at the Surface of an FeS₂/Carbon Nanotube Modified Glassy Carbon Electrode in Aqueous Medium