2002
DOI: 10.1039/b111301c
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Determination of 4-aminophenol using the quartz crystal microbalance sensor

Abstract: In this paper we report a method for the determination of 4-aminophenol (4-AP) in solution using a quartz crystal microbalance (QCM) sensor. 4-AP reacts with (para-unsubstituted) phenols to form hydrophobic indophenol dye species that precipitate out and adsorb to the surface of the crystal to produce a shift in the crystal resonant frequency. This frequency change, due to in-situ indophenol mass adsorption, can be related to the initial 4-AP concentration. A range of phenols (namely o-cresol, 1-naphthol, reso… Show more

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Cited by 28 publications
(13 citation statements)
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“…Therefore, it is essential to develop simple, sensitive and accurate analytical methods for 4-AP detection in pharmaceutical preparations. Since 4-AP is an electroactive compound, considerable interests have been focused on the development of chemically modified electrodes for 4-AP detection [25][26][27][28][29][30].…”
Section: Introductionmentioning
confidence: 99%
“…Therefore, it is essential to develop simple, sensitive and accurate analytical methods for 4-AP detection in pharmaceutical preparations. Since 4-AP is an electroactive compound, considerable interests have been focused on the development of chemically modified electrodes for 4-AP detection [25][26][27][28][29][30].…”
Section: Introductionmentioning
confidence: 99%
“…Secondly, the data processing method should be developed instead of the commercial impedance analysis method [11,15]. Finally, a low bandwidth oscillator circuit is preferred instead of a broadband impedance analyzer [6,16]. …”
Section: Resultsmentioning
confidence: 99%
“…Additionally, traditional Resorcinol‐Formaldehyde (RF) carbon aerogels & Phenol‐Formaldehyde (PF) carbon aerogels are mostly non‐flexible brittle solids, with difficult to control microstructures. The monomer resorcinol is also a costly reagent, and its reaction with formaldehyde is tough to control owing to the higher activity for the two hydroxyl (‐OH) groups connected to the benzene ring, making it cumbersome for large scale commercial production …”
Section: Introductionmentioning
confidence: 99%