Determination of aflatoxin M1 (AFM1) in dairy sheep, goats and camel milk in Hail Region, Kingdom of Saudi Arabia and evaluation of different methods reducing its concentrations in milk

Alrashedi, Huda; Omer, Sawsan; Almutairi, Adibah; Al-Basher, Gadah; Mohammed, Osama

doi:10.1080/26395940.2023.2283056

Environmental Pollutants and Bioavailability

2023

DOI: 10.1080/26395940.2023.2283056

|View full text |Cite

Determination of aflatoxin M1 (AFM1) in dairy sheep, goats and camel milk in Hail Region, Kingdom of Saudi Arabia and evaluation of different methods reducing its concentrations in milk

Huda Alrashedi,

Sawsan Omer,

Adibah Almutairi

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article3

Relationship

Self Cite0

Independent3

Authors

Journals

Cited by 3 publications

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Human health risk assessment of aflatoxin M1 in various dairy products in Iran: A literature review

Massahi,

Omer,

Habibollahi

et al. 2024

Journal of Food Composition and Analysis

View full text Add to dashboard Cite

Human health risk assessment of aflatoxin M1 in various dairy products in Iran: A literature review

Massahi,

Omer,

Habibollahi

et al. 2024

Journal of Food Composition and Analysis

View full text Add to dashboard Cite

Elimination of aflatoxin M1 from milk: Current status, and potential outline of applicable mitigation procedures

Kolarič,

Minarovičová,

Lauková

et al. 2024

Trends in Food Science & Technology

View full text Add to dashboard Cite

Assessment of Human Health Risks from Aflatoxin M1 in Raw Milk: A Study from North Shewa Zone, Oromia Region, Ethiopia

Geleta,

Nugussa,

Faye

et al. 2024

Environ�Health�Insights

View full text Add to dashboard Cite

This research aimed to assess the levels of AFM1 and evaluate the associated health risks from raw milk samples collected randomly from four selected towns. Ninety (n = 90) raw milk samples were randomly collected from smallholder dairy farmers in the North Shewa Zone, with 23 samples from Fiche, 23 from G/Gurracha, 22 from Dagem, and 22 from Sululta. The concentrations of AFM1 in the raw milk samples were determined using high-performance liquid chromatography with fluorescence detection (HPLC-FLD) after purification via an immunoaffinity column (IAC). AFM1 was detected in 76 (84.4%) raw milk samples, with 53 (58.9%) exceeding the maximum permissible limit established by the European Commission, 0.0500 µg/L. The highest AFM1 content was 2.00 µg/L and the lowest was 0.0100 µg/L. Additionally, risk assessment was performed using the margin of exposure (MOE), estimated daily intake (EDI), hazard index (HI), and cancer risk (CR). The results indicated that based on the average contamination levels of the milk during the study period and typical consumption rates, the average EDI of the adult population to AFM1 ranged from 0.374 to 0.852 ng/kg body weight (bw) per day. The calculated MOE values were less than 10,000, indicating potential health concerns. The mean HI value determined in this study was 2.70, which also suggests adverse health effects. Furthermore, the estimated risk of developing hepatocellular carcinoma (HCC) due to AFM1 exposure from milk consumption among adults was calculated to be 0.00170 cases per 100 000 individuals yearly. This finding indicates a significant risk of HCC, which justifies its continuous monitoring of dairy products throughout the entire supply chain, from production to consumption. Furthermore, our research highlights the need for further investigation into the risks posed by AFM1 in children, given their higher levels of milk consumption relative to adults.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Determination of aflatoxin M1 (AFM1) in dairy sheep, goats and camel milk in Hail Region, Kingdom of Saudi Arabia and evaluation of different methods reducing its concentrations in milk

Cited by 3 publications

References 51 publications

Human health risk assessment of aflatoxin M1 in various dairy products in Iran: A literature review

Human health risk assessment of aflatoxin M1 in various dairy products in Iran: A literature review

Elimination of aflatoxin M1 from milk: Current status, and potential outline of applicable mitigation procedures

Assessment of Human Health Risks from Aflatoxin M1 in Raw Milk: A Study from North Shewa Zone, Oromia Region, Ethiopia

Contact Info

Product

Resources

About