Determination of amphetamines in biological samples using electro enhanced solid-phase microextraction-gas chromatography

Zeng, Jingbin; Chen, Jingjing; Li, Min; Subhan, Fazle; Chong, Fayun; Wen, Chongying; Yu, Jianfeng; Cui, Bingwen; Chen, Xi

doi:10.1016/j.jchromb.2015.07.016

Cited by 34 publications

(6 citation statements)

References 48 publications

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“…28 In the past few decades, researchers have developed a variety of analytical methods to detect METH, including high-performance liquid chromatography-mass spectrometry (HPLC-MS), 29 electrochemiluminescence (ECL), 30 and gas chromatography-mass spectrometry (GC-MS). 31 These methods are successful in the analysis of METH and other misused substances, but they are confined to the solution, and the analysis procedure is not only time-consuming but also expensive, requiring a large number of expensive instruments and a complex pretreatment and operation process. Because of their high accuracy, simple equipment, and easy operation, electrochemical biosensors are frequently utilized in target detection.…”

Section: ■ Introductionmentioning

confidence: 99%

Antibody-Conjugated Electrospun Nanofibers for Electrochemical Detection of Methamphetamine

Atik

Kilic

Horzum

et al. 2023

ACS Appl. Mater. Interfaces

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Multifunctional electrospun nanofibers (ENs) with improved properties have increased attention nowadays. Their insoluble forms in water with decreased hydrophobicity are desired for the immobilization of biological molecules. Also, the addition of functional groups on the backbone provides the conjugation of biomolecules onto the surface of ENs via covalent bonds to increase their stability. Here, poly(vinylidene fluoride) (PVDF) was chosen to prepare a platform, which is insoluble in water, and polyethylenimine (PEI) was used to add amine groups on the surface of ENs to bind biological molecules via covalent conjugation. So, PVDF-PEI nanofibers were prepared on a glassy carbon electrode to immobilize an antimethamphetamine antibody (Anti-METH) as a model biomolecule. The obtained PVDF-PEI/Anti-METH was used for the bioelectrochemical detection of methamphetamine (METH), a common illicit drug. Bioelectrochemical detection of METH on PVDF-PEI/Anti-METH-coated electrodes was carried out by voltammetry in the range of 2.0–50 ng/mL METH. Moreover, the effect of dansyl chloride (DNC) derivatization of METH on the sensitivity of PVDF-PEI/Anti-METH was tested. Finally, METH analysis was carried out in synthetic body fluids. The obtained results showed that PVDF-PEI ENs can be adopted as an immobilization matrix for the biorecognition elements of biobased detection systems, and the derivative of METH (METH-DNC) increased the sensitivity of PVDF-PEI/Anti-METH.

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Section: ■ Introductionmentioning

confidence: 99%

Antibody-Conjugated Electrospun Nanofibers for Electrochemical Detection of Methamphetamine

Atik

Kilic

Horzum

et al. 2023

ACS Appl. Mater. Interfaces

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“…In SPME methods, in addition to the type of extraction system, the coating plays a very important role in the extraction efficiency of the analytes. So far, various coatings have been introduced in SPME methods that include metal oxide conductive polymers, molecular imprinting polymers, carbon‐based materials, metal–organic frameworks, and ionic liquids . Among different types of sorbents used for the extraction of organic analytes, conducting polymers, polyaniline, polypyrrole, polythiophene (PTh) and its derivatives have attracted great attention due to their multi‐functional properties such as large surface area, the ability to establish π–π interactions, polar functional groups, and excellent chemical, mechanical, and thermal stability .…”

Section: Introductionmentioning

confidence: 99%

Electrochemically controlled fiber‐in‐tube solid‐phase microextraction method for the determination of trace amounts of antipsychotic drugs in biological samples

Shamsayei

Yamini

Asiabi

2018

J of Separation Science

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In this study, a novel 'fiber-in-tube' configuration was applied to electrochemically controlled fiber-in-tube solid-phase microextraction of antipsychotic drugs (perphenazine and chlorpromazine) from biological samples. To prepare an electrochemically controlled fiber-in-tube solid-phase microextraction column, first eight stainless-steel wires were placed into the stainless-steel column. Then, a nanostructured Cu-Cr-Al ternary layered double hydroxide/polythiophene coating was prepared on the inner surface of the stainless-steel tube and on the surfaces of the stainless-steel wires by a facile in situ electrodeposition method. The nanostructured coating exhibited enhanced long lifetime, good mechanical stability, high porosity, and large specific surface area compared with polythiophene and Cu-Cr-Al layered double hydroxide coatings. Under the optimal conditions, the limits of detection were in the range of 0.07-0.8 μg/L. This method showed good linearity for perphenazine and chlorpromazine in the ranges of 0.3-300 and 0.2-300 μg/L, respectively, with coefficients of determination more than 0.9982. The inter- and intra-assay precisions (RSD%, n = 3) were in the ranges of 3.0-5.1 and 2.5-4.5% at three concentration levels of 5, 25 and 50 μg/L, respectively. Finally, the method was applied for the analysis of the drugs in human urine and plasma samples.

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“…An ordered mesoporous carbon/Nafion was developed as a SPME coating, and possessed excellent extraction selectivity toward aromatic nonpolar compounds . It was also used for electro‐enhanced SPME for amphetamines in biological samples . Zheng et al.…”

Section: Introductionmentioning

confidence: 99%

Mesoporous titanium oxide with high‐specific surface area as a coating for in‐tube solid‐phase microextraction combined with high‐performance liquid chromatography for the analysis of polycyclic aromatic hydrocarbons

Wang

Feng

et al. 2017

J of Separation Science

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Stainless-steel wires coated with mesoporous titanium oxide were placed into a polyether ether ketone tube for in-tube solid-phase microextraction, and the coating sorbent was characterized by X-ray diffraction and scanning electron microscopy. It was combined with high-performance liquid chromatography to build an online system. Using eight polycyclic aromatic hydrocarbons as the analytes, some conditions including sample flow rate, sample volume, organic solvent content, and desorption time were investigated. Under optimum conditions, an online analysis method was established and provided good linearity (0.03-30 μg/L), low detection limits (0.01-0.10 μg/L), and high enrichment factors (77.6-678). The method was applied to determine target analytes in river water and water sample of coal ash, and the recoveries are in the range of 80.6-106.6 and 80.9-103.5%, respectively. Compared with estrogens and plasticizers, extraction coating shows better extraction efficiency for polycyclic aromatic hydrocarbons.

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Determination of amphetamines in biological samples using electro enhanced solid-phase microextraction-gas chromatography

Cited by 34 publications

References 48 publications

Antibody-Conjugated Electrospun Nanofibers for Electrochemical Detection of Methamphetamine

Antibody-Conjugated Electrospun Nanofibers for Electrochemical Detection of Methamphetamine

Electrochemically controlled fiber‐in‐tube solid‐phase microextraction method for the determination of trace amounts of antipsychotic drugs in biological samples

Mesoporous titanium oxide with high‐specific surface area as a coating for in‐tube solid‐phase microextraction combined with high‐performance liquid chromatography for the analysis of polycyclic aromatic hydrocarbons

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