Determination of antiovarian antibodies after laparoscopic ovarian electrocauterization in patients with polycystic ovary syndrome

Serum anti-carbonic anhydrase I and II antibodies and polycystic ovary syndrome

“…The Androgen Excess Society proposed that PCOS should be diagnosed by the presence of three features: androgen excess (clinical and/or biochemical hyperandrogenism), ovarian dysfunction (oligo-anovulation and/or polycystic ovarian morphology), and exclusion of other androgen excess or ovulatory disorders [2]. Although exact pathophysiological mechanisms are not clear, premature adrenarche, obesity, insulin resistance, type 2 diabetes mellitus, endometrial carcinoma, ovulatory dysfunction, androgen excess, polycystic ovaries, complex genetic trait, cardiovascular disease and metabolic syndrome were associated with PCOS [3][4][5][6].…”

Serum Levels of Anti-histone and Anti-double-Strand DNA Antibodies Before and After Laparoscopic Ovarian Drilling in Women with Polycystic Ovarian Syndrome

“…Although these antibodies appeared in the sera of the patients after operation, their quantitative value was not significant. Thus they concluded that this laparoscopic procedure does not result in increased levels of AOA [7].…”

“…However, several studies have demonstrated its efficacy in treatment of infertility in PCOS [7,13]. Peritubal adhesion leading to infertility is the most important complication of this procedure being studied to a great extend [5,6].…”

“…It is also postulated that inflammation causes alterations of normal antigens to abnormal ones which stimulate immune system to produce anti-ovarian antibodies. In this regards Alborzi et al [7] examined this hypothesis by measuring anti-ovarian antibodies (AOA) in clomiphen-resistant PCOS patients before and after ovarian elecrocauterization. However, they found that this laparoscopic procedure does not result in increased levels of AOA.…”

Quantitative trait locus analysis of ovarian cysts derived from rete ovarii in MRL/MpJ mice

“…In women of childbearing age, most functional ovarian cysts are also derived from follicles, as evidenced by polycystic ovarian syndrome (PCOS) (Brassard et al 2008). Interestingly, PCOS has been known to be closely associated with not only metabolic syndrome and sex-hormone imbalance but also with autoimmune diseases (Alborzi et al 2009). Inevitably, multiple studies have used murine models to identify candidate genes or exacerbating factors in follicular cysts (Devin et In contrast, the genetic basis of nonfunctional ovarian cysts derived from epithelium has not been well established.…”