Determination of antioxidant activity, total phenolics and fatty acids in essential oils and other extracts from callus culture, seeds and leaves of Argania spinosa (L.) Skeels

Koufan, Meriyem; Belkoura, I.; Mazri, Mouaad Amine; Amarraque, Abderrahim; Essatte, Amine; Elhorri, Hafsa; Zaddoug, Fatima; Alaoui, Tajlmolk

doi:10.1007/s11240-020-01782-w

Cited by 39 publications

(17 citation statements)

References 57 publications

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“…Differentiated (organogenesis) and undifferentiated (callus) culture systems have been applied for in vitro production of the bioactive compounds of medicinal plants. Callus cultures have great potential for sustainable production of bioactive compounds of medicinal plants (Koufan et al 2020). However, undifferentiated calluses are not as promising as organogenesis cultures in terms of SMs production (Santos et al 2020).…”

Section: Discussionmentioning

confidence: 99%

“…However, undifferentiated calluses are not as promising as organogenesis cultures in terms of SMs production (Santos et al 2020). The superiority of differentiated cultures over the callus culture systems, in terms of level of produced bioactive compounds, has been reported in Schisandra henryi (Jafernik et al 2020), Phellodendron chinense (He et al 2020) and Argania spinosa (L.) (Koufan et al 2020). These observations could be due to the effect of developmental factors on SMs of medicinal plants, as the major of secondary metabolites often occur at a certain stage of plant growth.…”

Section: Discussionmentioning

confidence: 99%

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Integrative effects of stress- and stress tolerance-inducing elicitors on in vitro bioactive compounds of ajowan [Trachyspermum ammi (L.) Sprague] medicinal plant

Niazian

Howyzeh

Sadat-Noori

2021

Plant Cell Tiss Organ Cult

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Bioactive compounds of medicinal plants have a wide range of applications in pharmaceutical, food and other industries. In vitro culture systems have great potential for sustainable production of bioactive compounds of medicinal plants. In the present study, the individual and combined effects of a stress tolerance-inducing (salicylic acid) and a stress-inducing elicitor (polyethylene glycol) were evaluated on regeneration e ciency, antioxidants activity and phytochemical pro le of in vitro shoot cultures of ajowan. Different concentrations of salicylic acid (SA) (0, 10, 20, 40, 80 µM) and polyethylene glycol (PEG 6000) (0, 1, 2, 5%) were added to the shoot regeneration Murashige and Skoog medium containing Kin (1.5 mg/L) and NAA (0.25 mg/L) plant growth regulators. Salicylic acid reduced the adverse effect of PEG treatment on number of regenerated shoots and in vitro rooting. The activities of catalase, superoxide dismutase, and peroxidase enzymatic antioxidants were signi cantly increased in SA + PEG treated plants. The gas chromatography-mass spectrometry (GC-MS)-pro ling revealed quantitative and qualitative phytochemical differences between control and SA + PEG treated plants. The greatest means of p-cymene and thymol bioactive compounds were obtained from in vitro shoots treated with 5% PEG + 40 µM SA. The inter-simple sequence repeats (ISSR) markers proved the genetic stability of in vitro regenerated plants. The presented protocol is useful for large-scale sustainable production of secondary metabolites (SMs) of medicinal plants. The same strategy (stress tolerance-inducing elicitor + stress-inducing elicitor) is applicable to increase valuable SMs in other production systems such as hydroponic, greenhouse and eld conditions.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Integrative effects of stress- and stress tolerance-inducing elicitors on in vitro bioactive compounds of ajowan [Trachyspermum ammi (L.) Sprague] medicinal plant

Niazian

Howyzeh

Sadat-Noori

2021

Plant Cell Tiss Organ Cult

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“…Abundant studies showing that this tree possesses many secondary metabolites including avonoids, polyphenols, tannins saponins, alkaloids, quinones, anthraquinones cyanidins, terpenoids, sterols, mucilage, sesquiterpenes, reducing sugars, glucosides, carbohydrates and vitamin E. Thereby, the Argan tree has been subjected to many pharmacological screenings. There is evidence of their wide spectrum of in vitro, and in vivo biological activities including antioxidant (Koufan et al, 2020), anti-in ammatory (Kamal et al, 2019), antidiabetic (Hebi et al, 2018), antibacterial (Bonvicini et l., 2017), anti-fungal (El Abbassi et al, 2014), anticancer (Khallouki et al, 2017), antiviral (including anti-HIV) (Dzubak et al, 2006) and antimalarial (El Babili et al, 2010) activities.…”

Section: Argania Spinosamentioning

confidence: 99%

In silico screening of Moroccan medicinal plants with the ability to directly inhibit the novel coronavirus, SARS-CoV-2

Mrid

Bouchmaa

Kabach³

et al. 2020

Preprint

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Abstract In the present study, we investigated natural compounds contained in Moroccan medicinal plants and that might be used as natural inhibitors of the novel coronavirus, SARS-CoV-2, that causes coronavirus disease 2019 (COVID-19). We first performed a literature search for natural inhibitors of SARS or MERS coronaviruses. We then selected natural compounds that have been biologically tested and confirmed to possess anti-coronavirus activity. Subsequently, we used a molecular docking to determine whether the selected molecules could interact with the virus proteins. The compounds selected from virtual screening were then subjected to an in-silico analysis of absorption, distribution, metabolism and excretion (ADME) properties to select only natural compounds that could be orally bioavailable. Thereafter, a second search has been launched to select Moroccan medicinal plants that contain at least 3 molecules from those natural compounds. As results, among 41 natural inhibitors of SARS or MERS coronaviruses, only 13 have been successfully passed the ADME filtering. These molecules, showed abilities to interact with the novel coronavirus as it was predicted. Using these molecules and based on the data extracted from literature, 29 Moroccan medicinal plants have been found to contain at least 3 of these coronavirus inhibitors. Therefore, the medicinal plants selected in this study might contain direct anti-SARS-CoV-2 compounds.

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“…[9,10] A rapid phytochemical analysis study was also performed to find out the chemical compounds present in the Argan essential oil, which plays a key role in determining the antimicrobial efficacy of the Argan essential oil. [11,12]…”

Section: Original Articlementioning

confidence: 99%

“…The phytochemical properties analysis of the Argan essential oil procured from the local market was determined by the following methodologies. [11][12][13][14] 1. Wagner's test A drop of Argan essential oil was mixed with a drop of potassium iodide and iodine resulting in the formation of a reddish brown precipitate which indicates the presence of alkaloids in the oil.…”

Section: Phytochemical Analysis Of the Argan Essential Oilmentioning

confidence: 99%

Untitled

Iqubal¹

2020

IJGP

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Background: The aim of this study to focus on these tinea infections caused by the mold Trichophyton rubrum by collecting the clinical specimens by means of skin scraping samples from the affected sites of the patients and to evaluate the susceptibility of the isolates of the obtained clinical specimens toward the Argan essential oil. A rapid phytochemical analysis study was also performed. Materials and Methods: Argan essential oil procured from Jeddah local market, clinical skin scrape samples from the patient. The phytochemical study was done to find out the chemical compounds present in the Argan essential oil, which plays a key role in determining the antimicrobial efficacy of the Argan essential oil. Results and Discussion: The interpretation of the observation and results for the Argan essential oil showed the promising study results. Regarding its efficacy as potential antifungal agents when compared to that of the standard synthetic chemical agents used against the clinical skin scrape isolates of T. rubrum. Conclusion: The phytochemical compounds present in the Argan essential oil acts as an effective remedy toward the clinical skin scrape isolates of T. rubrum compared to the standard antifungal agents.

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Determination of antioxidant activity, total phenolics and fatty acids in essential oils and other extracts from callus culture, seeds and leaves of Argania spinosa (L.) Skeels

Cited by 39 publications

References 57 publications

Integrative effects of stress- and stress tolerance-inducing elicitors on in vitro bioactive compounds of ajowan [Trachyspermum ammi (L.) Sprague] medicinal plant

Integrative effects of stress- and stress tolerance-inducing elicitors on in vitro bioactive compounds of ajowan [Trachyspermum ammi (L.) Sprague] medicinal plant

In silico screening of Moroccan medicinal plants with the ability to directly inhibit the novel coronavirus, SARS-CoV-2

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