Determination of Arsenobetaine in Manufactured Seafood Products by Liquid Chromatography, Microwave-assisted Oxidation and Hydride Generation Atomic Absorption Spectrometry

Vélez, Dinoraz; Ybáñez, N.; Montoro, R.

doi:10.1039/a602769e

Cited by 45 publications

(33 citation statements)

References 24 publications

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“…At lest two studies from Chile and Brazil have found high amount of As in different species of fish that exceeds FAO/WHO recommended value and current guideline set by Brazil (Lavanchy Dougnac, 1999) (Macedo, 2010). Food preparation with As contaminated water has also found to increase As content in cooked food (Ackerman et al, 2005; Munoz et al, 2002; Navoni JA et al, 2007; Vélez et al, 1997). In order to reduce risk of As exposure and accurately assess As exposure, As contamination from food needs to be given more attention.…”

Section: Introductionmentioning

confidence: 99%

Arsenic exposure in Latin America: Biomarkers, risk assessments and related health effects

McClintock

Chen

Bundschuh

et al. 2012

Science of The Total Environment

162

106

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In Latin America, several regions have a long history of widespread arsenic (As) contamination from both natural and anthropological sources. Yet, relatively little is known about the extent of As exposure from drinking water and its related health consequences in these countries. It has been estimated that at least 4.5 million people in Latin America are chronically exposed to high levels of As (>50µg/L), some to as high as 2000 µg/L - 200 times higher than the World Health Organization (WHO) provisional standard for drinking water. We conducted a systematic review of 82 peer reviewed papers and reports to fully explore the current understanding of As exposure and its health effects, as well as the influence of genetic factors that modulate those effects in the populations of Latin America. Despite some methodological limitations, these studies suggested important links between high levels of chronic As exposure and elevated risks of numerous adverse health outcomes in Latin America - including internal and external cancers, reproductive outcomes, and childhood cognitive function. Several studies demonstrated genetic polymorphisms that influence susceptibility to these and other disease states through their modulation of As metabolism, with As methyltransferase (AS3MT), glutathione S-transferase (GST), and genes of one-carbon metabolism being specifically implicated. While the full extent and nature of the health burden are yet to be known in Latin America, these studies have significantly enriched knowledge of As toxicity and led to subsequent research. Targeted future studies will not only yield a better understanding of the public health impact of As in Latin America populations, but also allow for effective and timely mitigation efforts.

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Section: Introductionmentioning

confidence: 99%

Arsenic exposure in Latin America: Biomarkers, risk assessments and related health effects

McClintock

Chen

Bundschuh

et al. 2012

Science of The Total Environment

162

106

View full text Add to dashboard Cite

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“…84,[125][126][127][128][129][130][131] Cation-exchange HPLC has been less popular. The concentration of buffers used in anion-exchange (AE) chromatography of proteins often exceeds 0.1 M. Their use may result in variations of the detector's sensitivity because of the clogging of the nebulizer and sampler and skimmer cones.…”

Section: Ion-exchange Chromatographymentioning

confidence: 99%

“…This can be achieved thermochemically, 277 by microwave-assisted oxidation 127,267,278 or by UV photo-oxidation. The prerequisite for success is the conversion of organoarsenic species into AsH 3 .…”

Section: Detection Of Organoarsenic Speciesmentioning

confidence: 99%

Bio-inorganic speciation analysis by hyphenated techniques

Szpunar

2000

Analyst

279

197

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International audienceThe state-of-the-art of species-selective analysis for trace metals and metalloids in biological materials by chromatographic and electrophoretic separation techniques with element selective detection is critically reviewed. The species of interest include organoarsenic, organoselenium and metal complexes with bioglands such as phytochelatins, metallothioneins, proteins and polysaccharides. The separation mechanisms discussed include size-exclusion, anion- and cation-exchange and reversed-phase HPLC and flatbed and capillary zone electrophoresis. Advantages and limitations of various element selective (e.g. AAS, ICP-AES and ICP-MS) and molecule specific (electrospray MS/MS) detection techniques used on- and off-line are discussed. The applications of coupled techniques to the analysis of biological materials are comprehensively reviewed in tabular form. Attention is paid to the sample preparation and sources of error in bioinorganic speciation analysis

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“…Existem, na literatura, inúmeras aplicações da técnica de geração de hidretos com detecção por espectrometria atômica, em uma ampla variedade de amostras: alimentos (As) [163][164][165][166] ; água (As) 6,[167][168][169][170][171][172] , (Pb) 173 , (Sn) 174 , (Sb) [175][176][177] , (Se) [178][179][180] , (Tl) 181 , (As e Se) 182 , (As, Se e Sb) 183 , (As, Se, Sb e Ge) 184 ; água e solo (Pb) 185 , amostras ambientais (As) 186 , (Cd) 187 , (Sb) 188,189 , (Sn) 190 ; amostras biológicas (Se) 7 , (As e Bi) 191 ; amostras biológicas e ambientais (As) 192 , (Cd) 193 , (As e Se) 194 ; amostras clíni-cas: cabelo (Se) 195 , (Sb) 196 , urina (As) [197][198][199][200][201] , (Bi) 202 , (Se) 203,205 ; bebidas: vinho (Sb) 206 , vinho e cerveja (As) 207<...>…”

Section: Aplicaçõesunclassified

A geração química de vapor em espectrometria atômica

et al. 2002

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Recebido em 17/9/01; aceito em 29/5/02 CHEMICAL VAPOR GENERATION IN ATOMIC SPECTROMETRY. The historical development of atomic spectrometry techniques based on chemical vapor generation by both batch and flow injection sampling formats is presented. Detection via atomic absorption spectrometry (AAS), microwave induced plasma optical emission spectrometry (MIP-OES), inductively coupled plasma optical emission spectrometry (ICP-OES) , inductively coupled plasma mass spectrometry (ICP-MS) and furnace atomic nonthermal excitation spectrometry (FANES) are considered. Hydride generation is separately considered in contrast to other methods of generation of volatile derivatives. Hg -CVAAS (cold vapor atomic absorption spectrometry) is not considered here. The current state-of-the-art, including extension, advantages and limitations of this approach is discussed.Keywords: chemical vapor generation; atomic spectrometry; batch and flow injection. INTRODUÇÃOO sucesso da espectrometria atômica depende, freqüentemente, do procedimento de introdução da amostra, sendo que o modo mais comum baseia-se na formação de um aerossol líquido, por meio de nebulizadores pneumáticos. Esses dispositivos são de operação simples e conveniente e, por isso mesmo, amplamente utilizados. Entretanto, menos de 10% da solução introduzida é transformada em aerossol útil, sendo sua maior parte, portanto, descartada. Além disso, dificuldades com esses nebulizadores surgem quando são usadas soluções muito viscosas ou com alto teor salino ou, ainda, quando se dispõe tão somente de micro-volumes de amostra 1 .Uma alternativa que se apresenta é a transformação da espécie de interesse em um composto volátil, e seu posterior transporte para a célula de atomização. Quando esta transformação se faz por meio de uma reação química, o processo é conhecido como geração química de vapor. A geração eletroquímica também é citada, embora menos freqüentemente 2-7 . Dois trabalhos podem ser considerados como marcos na geração química de vapor: no primeiro, Hatch e Ott 8 inauguraram a técnica hoje conhecida como "de vapor frio", embora se deva citar os trabalhos anteriores de Poluektov et al. 9,10 Na técnica do vapor frio, o íon mercúrico contido numa solução da amostra é reduzido a mercúrio elementar e assim carreado por uma corrente de gás (ar, N 2 ou Ar), borbulhada através da solução, para a célula de absorção; ou seja, o vapor formado pela reação já é o próprio vapor atômico. O segundo marco na geração de vapor é o trabalho de Holak 11 , onde o arsênio foi reduzido a arsina pela adição, à amostra ácida, de Zn metá-lico, e esta transportada para a chama de um aparelho de absorção atômica. O ganho em sensibilidade observado resulta da maior eficiência de transporte do analito, em comparação com a nebulização pneumática, uma vez que toda a arsina formada pode, em princípio, alcançar o atomizador, carreada por um fluxo de argônio ou nitrogênio e também pelo próprio gás hidrogênio gerado na reação. Entretanto, a atomização do arsênio usando chama convencional apresenta ...

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Determination of Arsenobetaine in Manufactured Seafood Products by Liquid Chromatography, Microwave-assisted Oxidation and Hydride Generation Atomic Absorption Spectrometry

Cited by 45 publications

References 24 publications

Arsenic exposure in Latin America: Biomarkers, risk assessments and related health effects

Arsenic exposure in Latin America: Biomarkers, risk assessments and related health effects

Bio-inorganic speciation analysis by hyphenated techniques

A geração química de vapor em espectrometria atômica

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