Determination of benzothiazoles, benzotriazoles and benzenesulfonamides in seafood using quick, easy, cheap, effective, rugged and safe extraction followed by gas chromatography - tandem mass spectrometry: Method development and risk assessment

Castro, Óscar; Borrull, Sílvia; Pocurull, Eva; Borrull, Francesc

doi:10.1016/j.chroma.2023.463841

Cited by 3 publications

(3 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The % R app obtained after the whole process was 31%, and the matrix effect was only − 1%. This method was compared with another method developed by our research group for determining benzothiazoles in fish using LipiFiltr® for cleaning-up [ 39 ]. LipiFiltr® is a cartridge that traps lipids and fats to purify the extract and make it suitable for analysis by GC–MS or LC–MS.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Selective determination of 2-aminobenzothiazole in environmental water and organic extracts from fish and dust samples

Moral,

Borrull,

Furton

et al. 2023

Anal Bioanal Chem

Self Cite

View full text Add to dashboard Cite

In the present study, a homemade mixed-mode ion-exchange sorbent based on silica with embedded graphene microparticles is applied for the selective extraction of 2-aminobenzothiazole (NH2BT) followed by determination through liquid chromatography coupled to high-resolution mass spectrometry. The sorbent was evaluated for the solid-phase extraction of NH2BT from environmental water samples (river, effluent wastewater, and influent wastewater), and NH2BT was strongly retained through the selective cation-exchange interactions. Therefore, the inclusion of a clean-up step of 7 mL of methanol provided good selectivity for the extraction of NH2BT. The apparent recoveries obtained for environmental water samples ranged from 62 to 69% and the matrix effect from −1 to −14%. The sorbent was also evaluated in the clean-up step of the organic extract for the extraction of NH2BT from organic extracts of indoor dust samples (10 mL of ethyl acetate from pressurized liquid extraction) and fish (10 mL of acetonitrile from QuEChERS extraction). The organic extracts were acidified (adding a 0.1% of formic acid) to promote the cation-exchange interactions between the sorbent and the analyte. The apparent recoveries for fish samples ranged from 22 to 36% depending on the species. In the case of indoor dust samples, the recovery was 41%. It should be highlighted the low matrix effect encountered in such complex samples, with values ranging from −7 to 5% for fish and dust samples. Finally, various samples were analyzed. The concentration in river samples ranged from 31 to 136 ng/L; in effluent wastewater samples, from 55 to 191 ng/L; in influent wastewater samples, from 131 to 549 ng/L; in fish samples, from 14 to 57 ng/g dried weight; and in indoor dust samples, from <MQL to 114 ng/g.

show abstract

Section: Resultsmentioning

confidence: 99%

“…Fish samples were acquired from markets in Tarragona (Spain), cleaned, frozen, and lyophilized using a miVac Duo sample concentrator with a SpeedTrap freeze-drying system evaporator (Genevac). The extraction method was adapted from a previous study [ 39 ]. The samples were ground and sieved (500 µm).…”

Section: Methodsmentioning

confidence: 99%

Selective determination of 2-aminobenzothiazole in environmental water and organic extracts from fish and dust samples

Moral,

Borrull,

Furton

et al. 2023

Anal Bioanal Chem

Self Cite

View full text Add to dashboard Cite

show abstract

“…Benzenesulfonamide (BSA) is a widely used compound in pharmaceuticals, agrochemicals, and material science [ 18 , 19 , 20 , 21 , 22 ]. Its characteristics have been the subject of numerous studies due to its importance as a building block for various applications [ 23 , 24 , 25 , 26 ]. Surprisingly, despite its importance, solubility has rarely been measured [ 27 , 28 ].…”

Section: Introductionmentioning

confidence: 99%

Finding the Right Solvent: A Novel Screening Protocol for Identifying Environmentally Friendly and Cost-Effective Options for Benzenesulfonamide

2023

View full text Add to dashboard Cite

This study investigated the solubility of benzenesulfonamide (BSA) as a model compound using experimental and computational methods. New experimental solubility data were collected in the solvents DMSO, DMF, 4FM, and their binary mixtures with water. The predictive model was constructed based on the best-performing regression models trained on available experimental data, and their hyperparameters were optimized using a newly developed Python code. To evaluate the models, a novel scoring function was formulated, considering not only the accuracy but also the bias–variance tradeoff through a learning curve analysis. An ensemble approach was adopted by selecting the top-performing regression models for test and validation subsets. The obtained model accurately back-calculated the experimental data and was used to predict the solubility of BSA in 2067 potential solvents. The analysis of the entire solvent space focused on the identification of solvents with high solubility, a low environmental impact, and affordability, leading to a refined list of potential candidates that meet all three requirements. The proposed procedure has general applicability and can significantly improve the quality and speed of experimental solvent screening.

show abstract

Comparison of the presence of high production volume chemicals in farmed and wild fish highly consumed in catalonia and their risk assessment

Borrull,

Pocurull

et al. 2024

Chemosphere

View full text Add to dashboard Cite

Determination of benzothiazoles, benzotriazoles and benzenesulfonamides in seafood using quick, easy, cheap, effective, rugged and safe extraction followed by gas chromatography - tandem mass spectrometry: Method development and risk assessment

Cited by 3 publications

References 34 publications

Selective determination of 2-aminobenzothiazole in environmental water and organic extracts from fish and dust samples

Selective determination of 2-aminobenzothiazole in environmental water and organic extracts from fish and dust samples

Finding the Right Solvent: A Novel Screening Protocol for Identifying Environmentally Friendly and Cost-Effective Options for Benzenesulfonamide

Comparison of the presence of high production volume chemicals in farmed and wild fish highly consumed in catalonia and their risk assessment

Contact Info

Product

Resources

About