Determination of Blood Ascorbic Acid

The Distribution of Ascorbic Acid Between Cells and Serum in Relation to Its Urinary Excretion

“…Determinations of the concentration of ascorbic acid in whole blood (1,2,3,4,5,6,7,8) and in plasma or serum (9,10,11,12,13,14,15,16,17,18) as well are believed to indicate the degree of saturation of the organism. No strict correlation, however, has been established between the ascorbic acid content of whole blood and of plasma, although the concentration in cells is consistently higher than in plasma under ordinary conditions (5).…”

Sobisminol Mass: Clinical Results With Oral Administration

“…Patients tend to be more regular in their treatment because many of them greatly fear the injection, with its attendant pain and discomfort. 6. Treatment accidents such as abscess and embolism are precluded.…”

“…All circumstantial evidence points to the fact that sobisminol mass (orally) will do whatever any other bismuth preparation will do, but the ultimate proof lies in a treated series observed for several years. 6. Oral therapy has the disadvantage that its effi¬ ciency depends on the intelligence and honesty of the patient (patients are frequently lax and dishonest to their own disadvantage).…”

The assessment of vitamin C nutrition in man

“…Mindlin & Butler, 1937-8]. Pijoan & Klemperer [1937] added KCN (5 mg.) to inhibit oxidation of ascorbic acid in freshly drawn venous blood. Barron, Barron & Klemperer [1936] considered that addition of KCN may enhance the ascorbic acid value.…”