Determination of bromine in blood serum by neutron activation analysis and x-ray spectrometry

Abstract

A method is described for the nondestructive determination of bromine in blood serum by INAA followed by X-ray spectrometry. The use of magnetic fields for the elimination of the particles emitted by the blood matrix reduces the background and makes possible the accurate measurement of the bromine X-rays. An average value of 7.38 f 0.44 mg Br/L blood serum was obtained for the single person tested.

Bromide [Biomonitoring Methods, 2006]

“…Exact data on the precision, accuracy and sources of interference permit the establishment of a robust routine measurement procedure. Compared with other recognised methods for bromide assay, such as X-ray fluorescence analysis [6,24], neutron activation analysis [25], ICP-MS [4] and ion chromatography [26], the method described here is remarkable, as it does not require apparatus of great technical complexity. Thus exact and valid bromide measurements can be performed, even in a simply equipped laboratory.…”