The integration of innovative equipment technologies in production processes offers efficiency potentials with regards to energy and resource demand as well as investment and operating costs. For the estimation of these potentials, a sufficiently detailed database is necessary as well as the possibility to consider particular boundary conditions of the production process, infrastructure of the production site, and the overall plant design. A structured concept for the selection of suitable equipment technol-ogies and sizing rules for the design of the equipment for a desired process task are presented in this review. The combination with an appropriate modeling approach allows a holistic assessment of technically feasible solutions to quantify economic and ecological efficiency potentials of the equipment technologies. The application of this concept is demonstrated on the task of a typical heat transfer problem in the special chemicals sector.