1995
DOI: 10.1016/0731-7085(95)01284-r
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Determination of cocaine and its metabolites in human urine by gas chromatography/mass spectrometry after simultaneous use of cocaine and ethanol

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Cited by 24 publications
(20 citation statements)
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“…Cocaine and ethanol are frequently taken together with CE having a much longer lasting high (50). CE is even more toxic than cocaine, and its potency results in an increased risk of death from overdose (51).…”
Section: Discussionmentioning
confidence: 99%
“…Cocaine and ethanol are frequently taken together with CE having a much longer lasting high (50). CE is even more toxic than cocaine, and its potency results in an increased risk of death from overdose (51).…”
Section: Discussionmentioning
confidence: 99%
“…It has a biological activity on dopaminergic neurons similar to cocaine and acts on the same receptors. Moreover, it is at least equipotent to cocaine in stimulating motor activity (Dean et al, 1992;De La Torre et al, 1995;Jatlow et al, 1996). According to Harris et al (2003), about one-sixth of a cocaine dose is transformed into cocaethylene Gonzalez et al, 2002;l Musshoff et al, 2009. during human metabolism; the rate of biotransformation of cocaine to cocaethylene increases proportionally to the dosage.…”
Section: Cocainementioning
confidence: 99%
“…The concurrent use of COC and ethanol results in a biologically active molecule, cocaethylene (CE), which is nearly as psychoactive as COC but produces a more long lasting high [1][2][3]. Moreover, CE is even more toxic than COC, and its potency results in an increased risk of death due to overdose [4].…”
Section: Introductionmentioning
confidence: 98%