Determination of dapsone in meat and milk by liquid chromatography tandem mass spectrometry

Flow injection chemiluminescence sensor using core-shell molecularly imprinted polymers as recognition element for determination of dapsone

“…The monodispersed spherical SiO 2 were prepared by the hydrolysis of TEOS [32][33][34]. Typically, two solutions, I (5 mL of TEOS in 30 mL of EtOH) and II (9 mL of ammonia in 50 mL of EtOH), were prepared separately.…”

“…Up to now, some methods have been developed for the determination of DDS already such as liquid chromatography tandem mass spectrometry [34,35]. Unfortunately, the development of this method has been limited by the high expense of the instruments and high cost during the procedure.…”

Sensitive and Specific Lc-MS/MS Method for the Simultaneous Determination of Chlorproguanil, Dapsone, and Their Metabolites in Human Plasma

“…The instrument parameters, namely, capillary voltage, source block temperature, desolvation temperature, desolvation gas flow, and collision gas (Argon) pressure were set at 3.5 kV, 120 C, 350 C, 600 L hr À1 , and 2.93 e À3 mbar, respectively. The selected m=z transitions, [12,16,19] collision energy, and source cone voltage are reported in Table 1. The dwell time was 0.1 s for each transition.…”

“…[8,9,13,14,16] Recently Hadjigeorgiou et al [12] determined dapsone in meat and milk by homogenization of samples in alkaline conditions and organic solvent extraction followed by purification on silica gel solid phase extraction cartridges. The goal was to develop a simple and robust sample preparation method.…”

“…The HPLC methods for the determination of DDS and its metabolite, MADDS, in plasma, whole blood, [8,9] serum, and saliva, [10] and LC-MS= MS methods for the determination of DDS in muscle, [11] meat, and milk [12] have been reported. Determination of CPG and its metabolite, CCG, in human plasma, erythrocyte and urine [13,14] using HPLC has also been performed.…”