Determination of drugs of abuse and their metabolites in human plasma by liquid chromatography–mass spectrometry

Evaluation of a pharmacokinetic hypothesis for reduced locomotor stimulation from methamphetamine and cocaine in adolescent versus adult male C57BL/6J mice

“…General LC/MS procedures followed Concheiro et al (2006). An Agilent 1100 series LC system (Santa Clara, CA, USA) was used for sample separation and introduction to mass spectrometry.…”

Determination of Illicit Drugs in Urine and Plasma by Micro-SPE Followed by HPLC–MS/MS

“…In addition to the serious toxicological and social risks for people using these substances, they also present a great threat for non-users potentially in contact with users, for example during driving or in the workplaces. Concern over driving under the influence of drugs (DUID) [1] as a risk factor and a cause of road accidents has recently risen, as illicit drugs can influence the human behaviour in different ways [2]. Confirmation of identity of forensically relevant compounds, such as drugs of abuse, is a necessary step in medico-legal controls of people involved in crimes, workplace accidents and DUID.…”

Analysis of Illicit Drugs in Water Using Direct‐Injection Liquid Chromatography‐Tandem Mass Spectrometry

“…LC−MS/MS analysis (Concheiro et al, 2006;Cheze et al, 2007;Johansen and Bhatia, 2007;Kronstrand et al, 2004;Scheidweiler and Huestis, 2004), especially if the sample has been further extracted and concentrated. Solid-phase extraction (SPE), on-line SPE, and liquid−liquid extractions are commonly used methods for illicit drugs in water or liquid matrices Barcelo et al, 2008;van Nuijs et al, 2009;Deventer et al, 2006;Concheiro et al, 2007).…”