Determination of epichlorohydrin in blood by gas chromatography and selected ion monitoring

Selective epichlorohydrin-sensing performance of Ag nanoparticles decorated porous SnO2architectures

“…Gas chromatography, gas chromatography-mass a Key Laboratory for Photonic and Electronic Bandgap Materials, Ministry of spectrometry, solid phase microextraction and headspace gas chromatography methods have been developed and validated for the determination for ECH. [25][26][27][28][29][30] Metal oxide based chemiresistive gas sensors are easy to incorporate into portable real-time detectors of ECH gas because of their miniaturized size, low cost, simplicity of fabrication, and fast operation. [31][32][33] In the present study, Ag NPs decorated porous SnO 2 structures as low concentration ECH gas sensing detectors were studied.…”

Determination of Epichlorohydrin in Active Pharmaceutical Ingredients by Gas Chromatography–Mass Spectrometry

“…Various analytical techniques can be used for the determination of ECH. However, due to the chemical characteristics of ECH, the method of choice is often gas chromatography (GC), with either electron capture detection (ECD) or mass spectrometric detection. − In this paper we present a GC–MS method for the detection and quantitation of ECH in a new API. The method was fully validated in accordance with in-house validation guidelines for trace level analysis method, and its applicability was demonstrated by analysis of real-life samples.…”