Determination of Formaldehyde in Water by High Performance Liquid Chromatography With the Use of Solid Phase Extraction

Kochetkov, P. P.; Malysheva, Alla G.; Глебов, В В

doi:10.18821/0016-9900-2017-96-3-281-284

Cited by 4 publications

(2 citation statements)

References 5 publications

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“…Одним из наиболее мощных и универсальных методов исследования структуры неизвестных веществ является жидкостная хромато-масс-спектрометрия (ЖХ-МС/МС) [27,28], сочетающая наряду с высокой чувствительностью возможность проведения высокоселективного разделения смесей и идентификацию веществ по сигналам ионов-предшественников и ионов-продуктов по масс-спектрам. Специфичность метода основывается на том, что детектирование происходит индивидуально для каждого вещества, а избирательность достигается за счёт подбора условий хроматографического разделения и детектирования [29][30][31].…”

Section: Introductionunclassified

“…Кроме того, учитывая существующие гигиенические нормативы содержания триазиновых пестицидов в воде в соответствии с СанПиН 2.1.4.1116-02 1 , данный диапазон определения в отношении чувствительности не пригоден для контроля качества и безопасности бутилированной питьевой воды. Целью настоящего исследования являлось усовершенствование в части повышения чувствительности методики [29], использующей метод ВЭЖХ-МС/МС, для определения триазиновых пестицидов в воде.…”

Section: Introductionunclassified

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High-sensitive separate determination of the group of triazine pesticides in drinking water by the method of high performance liquid chromatography with tandem mass-spectrometrical detection

Kochetkov¹,

Георгиевна²,

Глебов

et al. 2020

Hygiene and Sanitation

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Introduction. The modern highly sensitive methods of controlling substances that affect humans in real environmental conditions are necessary to adequately assess the quality and chemical safety of drinking water, including pesticides used in agriculture for the destruction of weeds and pests. The aim of the work was to improve the sensitivity of existing techniques for the determination of triazine pesticides in their joint presence to control drinking and bottled water. Material and methods. The studies were performed using a chromatography mass-spectrometric system including a liquid chromatography with tandem mass-spectrometric triple quadrupole detector. Results. The influence of various factors on the extraction of triazine pesticides from water has been studied, the chromatographic and detection conditions have been optimized. Linearity in the range of 0.1 - 10 μg / dm3 is proved. The limits of detection and quantitative determination of triazine pesticides in drinking water are established in accordance with hygienic standards. Discussion. The procedure allows separate determination of triazine pesticides when they are co-located in concentrations at and below the corresponding MPC values in drinking and bottled water. The method allows reliably determining the target compounds without the use of hard-to-reach deuterated reference materials. To improve the reliability of the method, as an internal standard it is recommended to use one of the compounds studied, which is not a widely used pesticide, for example, propazine, with mandatory control of the initial matrix for its content. Conclusion. A highly sensitive method for the separate determination of a group of triazine pesticides (simazine, atrazine, propazine, prometrin, metribuzin, metamitron) was developed with their joint presence in drinking water with sensitivity at or below the corresponding hygienic standards.

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Section: Introductionunclassified

High-sensitive separate determination of the group of triazine pesticides in drinking water by the method of high performance liquid chromatography with tandem mass-spectrometrical detection

Kochetkov¹,

Георгиевна²,

Глебов

et al. 2020

Hygiene and Sanitation

Self Cite

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Vertical Distribution of Cs-137 in Soils of Orel Region 30 Years after Chernobyl Accident

Kulieva

Berezkin

Аскарова

et al. 2020

IOP Conf. Ser.: Mater. Sci. Eng.

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The article presents the first results of the study of vertical redistribution of Radiocaesium in different types of agricultural soils of the Orel region, performed in the period 2016-2017. Orel region, one of the 19 regions of Russia, where as a result of the Chernobyl accident (1986) large areas were contaminated with various radionuclides, including Cs-137, with soil contamination level Cs-137 above 1 Ki/km2 (37 kBq/m2). The work was carried out as a private initiative study within the field teaching and scientific practice of the Ecology Faculty of the Peoples’ Friendship University of Russia (RUDN). It was found that the main stock of Radiocaesium falls on the top 20 cm of arable soils. Despite the overall reduction in dose over 30 years, Radiocaesium is still traceable to a depth of 40-50 cm, depending on soil type, organic matter content, particle size distribution and other factors.

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Application of Mathematical Planning of the Experiment in the Choosing the Optimum Conditions of the Vapor-Phase Gas-Chromatographic Determination of Formaldehyde in the Urine

Alekseenko

Zhurba

2018

HAS

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Introduction. There was substantiated a method for the determination of formaldehyde by vapor-phase gas chromatography by the use of derivatizing reagent o-(2,3,4,5,6-pentafluorbenzyl)hydroxylamine. Material and methods. Formaldehyde in urine was derivatized to o-pentafluorobenzyloxime and recovered to the vapor phase by heating the urine sample with o-(2,3,4,5,6-pentafluorbenzyl)hydroxylamine in a sealed vial. Gas-chromatographic analysis of the vapor-air phase was performed in a mode of the temperature gradient on a capillary column HP-5 with a flame ionization detector. Identification of the analyte in the form of the derivative-o- pentafluorobenzyloxime of formaldehyde was carried out according to the absolute retention time, which was established by comparing the chromatograms of model formaldehyde mixtures in the urine of different concentrations. Results. The optimal conditions for gas extraction are selected using mathematical experimental planning. The most important factors of gas extraction in the vapor-phase analysis are the temperature and time of the establishment of the interphase equilibrium with heating. From the experimentally obtained curves of the analytical signal on the temperature and the heating time, the zero level and the interval of variation of these factors are chosen. A matrix for planning a 2-factor experiment was constructed. The coefficients of the mathematical model are determined. There was carried out statistical processing of the experimental data, which was reduced to the estimation of the reproducibility of the optimization parameter and to the evaluation of the significance of the coefficient of the mathematical model. The adequacy of the mathematical model was evaluated, its interpretation was carried out. Discussion. The peak area of the analyte increases with the elevating the temperature and heating time, due to an increase in the analyte concentration in the vapor phase. Moreover, the heating time makes a greater contribution to the formation of the analytical signal than the temperature. The step of motion along the gradient was calculated and the experiments of steep ascent were carried out. Conclusion. According to the results of the steep ascent experiments, the optimal conditions for the gas extraction of formaldehyde in the form of a derivative were chosen.

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Determination of Formaldehyde in Water by High Performance Liquid Chromatography With the Use of Solid Phase Extraction

Cited by 4 publications

References 5 publications

High-sensitive separate determination of the group of triazine pesticides in drinking water by the method of high performance liquid chromatography with tandem mass-spectrometrical detection

High-sensitive separate determination of the group of triazine pesticides in drinking water by the method of high performance liquid chromatography with tandem mass-spectrometrical detection

Vertical Distribution of Cs-137 in Soils of Orel Region 30 Years after Chernobyl Accident

Application of Mathematical Planning of the Experiment in the Choosing the Optimum Conditions of the Vapor-Phase Gas-Chromatographic Determination of Formaldehyde in the Urine

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