2013
DOI: 10.1007/s10812-013-9728-1
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Determination of heparin using terbium-danofloxacin as a luminescent probe

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Cited by 6 publications
(2 citation statements)
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“…Conventional clinical methods for heparin detection rely on the measurement of activated clotting time or activated partial thromboplastin time . Different methods have been developed for heparin measurement, including resonance Rayleigh scattering , fluorimetry (3,6‐8), electrochemical sensor (2,9‐11), capillary electrophoresis , high performance liquid chromatography (HPLC) and colorimetric methods . These methods are not sufficiently reliable and exact for clinical settings because of their lack of specificity and possible interference with other factors .…”
Section: Introductionmentioning
confidence: 99%
“…Conventional clinical methods for heparin detection rely on the measurement of activated clotting time or activated partial thromboplastin time . Different methods have been developed for heparin measurement, including resonance Rayleigh scattering , fluorimetry (3,6‐8), electrochemical sensor (2,9‐11), capillary electrophoresis , high performance liquid chromatography (HPLC) and colorimetric methods . These methods are not sufficiently reliable and exact for clinical settings because of their lack of specificity and possible interference with other factors .…”
Section: Introductionmentioning
confidence: 99%
“…This situation shows the need to identify heparin both in pharmaceuticals, and in the blood of patients. At present there are various methods capable of determining heparin in pharmaceuticals and biological fluids, namely: spectral [4,5], electrochemical [6,7], chromatographic [8,9], biochemical [10,11]. Unfortunately, these approaches require sophisticated instrumentation and expensive reagents, which frequently makes them hardly realizable in practice.…”
Section: Introductionmentioning
confidence: 99%