“…But the extraction step presents several disadvantages such as tedious steps, large sample and organic solvent volumes, low selectivity and reproducibility, and environmental pollution [9]. The most popular methods for detection and quantification of histamine, following extraction, are high-performance liquid chromatography (HPLC) [15], liquid chromatography coupled with mass spectrometry (LC-MS) [16], absorbance [17], and fluorometry [18,19]. Additionally, surface-enhanced Raman spectroscopy (SERS) [20][21][22], and ELISA [23,24], have also been intensely researched as alternative routes for histamine detection.…”