Hydrothermal alteration is one of the most important steps in the exploration of precious ore deposits. In this study, it is aimed to detect the hydrothermal alteration areas and mineral contents they preserve with ASTER and Hyperion satellite images and compare the obtained results. Because of the presence of intensive hydrothermal alteration and poor vegetation, the area which is located at the northern part of Zara district of Sivas Province has been chosen as the study area. Contact zones of Argillic (Kaolinite, illite), phyllic (serisite, muscovite) and propylitic (chlorite, calsite, epidote) alteration areas were detected with field studies, petrographic and geochemical investigations. The spectral signatures of hydrothermal minerals were measured via ASD spectroradiometer from the representative samples belonging to hydrothermal alteration study areas. According to the results, obtaining the hydrothermal alteration maps from ASTER and Hyperion satellite data are in coincide with the geological map.