“…Seven fully in vitro studies were published in the past two years, three using cadaveric pigs kidney model and two with living animal models (pigs) (Table 1). Various methods of IRP measurement were used: antegradely through percutaneous access [13,17–19], retrogradely aside from the scope [16,20,21,22 ▪▪ ] or through the fURS working channel [23,24] and using a robotic system [25]. Among this studies, IRP is decreased with a reduced inflow (occupied working channel) and an increased outflow (UAS insertion), except in Doizi et al study where a 10–12Fr UAS with 193 cmH 2 O was not associated with an IRP decrease [13,18,22 ▪▪ ,25].…”