Determination of natural phenols in olive fruits by chitosan assisted matrix solid-phase dispersion microextraction and ultrahigh performance liquid chromatography with quadrupole time-of-flight tandem mass spectrometry

Peng, Li-Qing; Qin, Li; Chang, Yan‐xu; An, Malaviya; Yang, Rui; Tan, Zhijing; Hao, Jie; Cao, Jun; Xu, Jingjing; Hu, Shuai-Shuai

doi:10.1016/j.chroma.2016.06.011

Cited by 58 publications

(27 citation statements)

References 33 publications

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“…The developed methodology has demonstrated to be better in terms of cost, simplicity and sample throughput compared with traditional methodologies for determination of OLE like HPLC and comparable in terms of sensitivity and robustness. Finally, Table lists the main analytical features obtained in the selected related works found in the literature involving the electrochemical sensing of OLE .…”

Section: Resultsmentioning

confidence: 99%

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Pencil graphite electrodes for improved electrochemical detection of oleuropein by the combination of Natural Deep Eutectic Solvents and graphene oxide

2017

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A novel methodology is presented for the enhanced electrochemical detection of oleuropein in complex plant matrices by Graphene Oxide Pencil Grahite Electrode (GOPGE) in combination with a buffer modified with a Natural Deep Eutectic Solvent, containing 10% (v/v) of Lactic acid, Glucose and H2O (LGH). The electrochemical behavior of oleuropein in the modified‐working buffer was examined using differential pulse voltammetry. The combination of both modifications, NADES modified buffer and nanomaterial modified electrode, LGH‐GOPGE, resulted on a signal enhancement of 5.3 times higher than the bare electrode with unmodified buffer. A calibration curve of oleuropein was performed between 0.10 to 37 μM and a good linearity was obtained with a correlation coefficient of 0.989. Detection and quantification limits of the method were obtained as 30 and 102 nM, respectively. In addition, precision studies indicated that the voltammetric method was sufficiently repeatable, %RSD 0.01 and 3.16 (n = 5) for potential and intensity, respectively. Finally, the proposed electrochemical sensor was successfully applied to the determination of oleuropein in an olive leaf extract prepared by ultrasound‐assisted extraction. The results obtained with the proposed electrochemical sensor were compared with Capillary Zone Electrophoresis analysis with satisfactory results.

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Section: Resultsmentioning

confidence: 99%

“…Reliable, sensitive and robust methodologies for the rapid determination of OLE in olive leaves, olive oil industry by‐products, functional foods and pharmaceuticals are needed. OLE has been determined by classical approaches, including liquid chromatography and electrochemical techniques .…”

Section: Introductionmentioning

confidence: 99%

Pencil graphite electrodes for improved electrochemical detection of oleuropein by the combination of Natural Deep Eutectic Solvents and graphene oxide

2017

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“…In recent years, there have been many applications of MSPD in the extraction of constituents in TCM samples. Several selected representative studies involving using MSPD in TCM extraction are summarized in Table 3, which contains the progress in sorbents and miniaturization of MSPD [69–85]. The selection of dispersing sorbent is a key factor in the MSPD process, which directly influences the extraction efficiency and selectivity of target analytes.…”

Section: Sorbent‐based Microextraction Techniquesmentioning

confidence: 99%

Modern microextraction techniques for natural products

Peng

2020

Electrophoresis

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Natural product analysis has gained wide attention in recent years, especially for herbal medicines, which contain complex ingredients and play a significant clinical role in the therapy of numerous diseases. The constituents of natural products are usually found at low concentrations, and the matrices are complex. Thus, the extraction of target compounds from natural products before analysis by analytical instruments is very significant for human health and its wide application. The commonly used traditional extraction methods are time‐consuming, using large amounts of sample and organic solvents, as well as expensive and inefficient. Recently, microextraction techniques have been used for natural product extraction to overcome the disadvantages of conventional extraction methods. In this paper, the successful applications of and recent developments in microextraction techniques including solvent‐based and sorbent‐based microextraction methods, in natural product analysis in recent years, especially in the last 5 years, are reviewed for the first time. Their features, advantages, disadvantages, and future development trends are also discussed.

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“…Conventional dispersing sorbents (silica gel, octadecylsilyl silica, neutral alumina, florisil, diatomaceous earth, etc.) were widely utilized due to their special structure, surface area, and pore size . The common dispersants are limited in selectivity and easily obstructed by non‐target compounds with similar characteristics.…”

Section: Introductionmentioning

confidence: 99%

Solid acids assisted matrix solid‐phase dispersion microextraction of alkaloids by capillary electrophoresis coupled with quadrupole time‐of‐flight mass spectrometry

Wang

Dong

Yang

et al. 2019

J of Separation Science

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The quantification of three alkaloids is important because quantitative study is a means of assessing the reliability of the experimental method, and three alkaloids of peimine, peiminine, and peimisine are main active ingredients in Chinese Pharmacopoeia 2015. An effective method based on the matrix solid-phase dispersion microextraction was developed for the extraction of alkaloid compounds in Fritillariae Thunbergii Bulbus. Target analytes were analyzed by capillary electrophoresis coupled with quadrupole time-of-flight mass spectrometry. The optimized experimental condition was that 50 mg Fritillariae Thunbergii Bulbus was blended homogeneously with 10 mg citric acid for 5 min. Two hundred microliters of water acidized by 1 mol/L hydrochloric acid (pH = 4.5) was selected to elute tested alkaloids. The results demonstrated that the investigated method had low limits of detection (1.32-1.59 ng/mL), good recoveries (86.63-98.12%), and reproducibility (relative standard deviations of peak areas < 0.87%). The proposed matrix solid-phase dispersion microextraction coupled with capillary electrophoresis combined with quadrupole time-of-flight mass spectrometry was successfully applied for the extraction of alkaloids in plants. K E Y W O R D Scapillary electrophoresis, isosteroidal alkaloids, matrix solid-phase dispersion microextraction, quadrupole time-of-flight mass spectrometry, traditional Chinese medicine

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Determination of natural phenols in olive fruits by chitosan assisted matrix solid-phase dispersion microextraction and ultrahigh performance liquid chromatography with quadrupole time-of-flight tandem mass spectrometry

Cited by 58 publications

References 33 publications

Pencil graphite electrodes for improved electrochemical detection of oleuropein by the combination of Natural Deep Eutectic Solvents and graphene oxide

Pencil graphite electrodes for improved electrochemical detection of oleuropein by the combination of Natural Deep Eutectic Solvents and graphene oxide

Modern microextraction techniques for natural products

Solid acids assisted matrix solid‐phase dispersion microextraction of alkaloids by capillary electrophoresis coupled with quadrupole time‐of‐flight mass spectrometry

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