Determination of netilmicin in plasma by HPLC

Santos, María Dolores; García, Estrella; López, Francisco González; Lanao, José M.; Domínguez-Gil, A

doi:10.1016/0731-7085(95)01331-e

Cited by 24 publications

(15 citation statements)

References 8 publications

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“…Derivatisation yields higher sensitivity. Several methods for the derivatisation of aminoglycosides have been reported in the literature [1][2][3][4][5][6]. The method used here was an adaptation of that used for the analysis of gentamicin [6], a similar aminoglycoside antibiotic.…”

Section: Methods Of Derivatisationmentioning

confidence: 99%

Shelf lives of aseptically prepared medicines—stability of netilmicin injection in polypropylene syringes

Rigge

Jones

2004

Journal of Pharmaceutical and Biomedical Analysis

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Section: Methods Of Derivatisationmentioning

confidence: 99%

Shelf lives of aseptically prepared medicines—stability of netilmicin injection in polypropylene syringes

Rigge

Jones

2004

Journal of Pharmaceutical and Biomedical Analysis

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“…The derivatizing solution was prepared fresh daily and was made up by dissolving 20 mg of o-phthaldialdehyde in a solution made of 2 mL of mercaptoethanol, 10 mL of ethanol, and 100 mL of borate buffer, pH ¼ 10.4 (19).…”

Section: Reprintsmentioning

confidence: 99%

Determination of Amikacin in Biological Tissues by HPLC

Santos

Sayalero

Zarzuelo

et al. 2002

Journal of Liquid Chromatography & Related Technologies

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A rapid, specific, and reliable technique has been developed for the determination of Amikacin in biological tissues by high performance liquid chromatography. The technique involves the use of reverse phase liquid chromatography employing methanol, water (69 : 21, v=v), and tripotassium EDTA (2.2 g=L) as the mobile phase and emission and excitation wavelengths of 360 nm and 435 nm, respectively; the range of concentrations used being 0.25-25 mg=mL.The techniques afford excellent linearity, accuracy, and within-and between-day precision for the concentration range studied, allowing it to be used in daily practice for the determination of Amikacin at the laboratory.

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“…The derivatizing solution was prepared fresh daily and was made up dissolving 20 mg of o-phthaldialdehyde in a solution made of 2 mL of mercaptoethanol, 10 mL of ethanol and 100 mL of borate buffer, pH ¼ 10.4 (19).…”

Section: Reprintsmentioning

confidence: 99%

Determination of Amikacin in Biological Tissues by HPLC

Santos

Sayalero

Zarzuelo

et al. 2002

Journal of Liquid Chromatography & Related Technologies

View full text Add to dashboard Cite

A rapid, specific, and reliable technique has been developed for the determination of Amikacin in biological tissues by high performance liquid chromatography. The technique involves the use of reverse phase liquid chromatography employing methanol, water (69 : 21, v=v), and tripotassium EDTA (2.2 g=L) as the mobile phase and emission and excitation wavelengths of 360 nm and 435 nm, respectively, the range of concentrations used being 0.25-25 mg=mL.The techniques afford excellent linearity, accuracy, and within-and between-day precision for the concentration range studied, allowing it to be used in daily practice for the determination of Amikacin at the laboratory.

show abstract

Determination of netilmicin in plasma by HPLC

Cited by 24 publications

References 8 publications

Shelf lives of aseptically prepared medicines—stability of netilmicin injection in polypropylene syringes

Shelf lives of aseptically prepared medicines—stability of netilmicin injection in polypropylene syringes

Determination of Amikacin in Biological Tissues by HPLC

Determination of Amikacin in Biological Tissues by HPLC

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