Determination of Nitrite Through <i>S</i>-Nitrosocaptopril Formation and Fluorescent Derivatization of Remaining Captopril Using <i>o</i>-Phthalaldehyde and Glycine

Li, Youxin; Zhang, Ying; Ali, Abd al-karim F.; Danielson, Neil D.

doi:10.1080/00032719.2018.1484470

Cited by 1 publication

(1 citation statement)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…-NO 2 [20][21][22][23], and CN − [24][25][26][27][28][29]. Although these sensors show great potential for ion sensing, their practical application is limited by drawbacks such as intrinsic toxicity, optical instability, water insolubility, and susceptibility to interference, especially those developed for the detection of CN − .…”

Section: Introductionmentioning

confidence: 99%

Copper nanoclusters with/without salicylaldehyde-modulation for multifunctional detection of mercury, cobalt, nitrite and cyanide ions in aqueous solution and bioimaging

Ding¹,

Chen²,

Cao³

et al. 2021

Nanotechnology

View full text Add to dashboard Cite

The sensitive determination of multiple heavy metal ions and toxic anions is important in biological and environmental fields. Here we report a facile strategy to construct a multifunctional chemosensor for the detection of Hg2+, NO 2 − Co2+, and CN− in aqueous solution based on the fluorescent copper nanoclusters (Cu NCs). It was interesting to find that salicylaldehyde (SA) could effectively modulate the fluorescence property and sensing behavior of Cu NCs. In the absence of SA, Cu NCs showed ‘on-off’ fluorescence responses at the addition of Hg2+ and NO 2 − under different quenching mechanisms. Upon the presence of SA, Cu NCs exhibited a strong intramolecular charge transfer emission at 500 nm, accompanied by the decrease of the initial fluorescence of Cu NCs at 430 nm. This fluorescence on-state of Cu NC–SA at 500 nm was found to be exclusively turned off by Co2+ and enhanced by CN−. Spectroscopy results combined with thermodynamic analysis provided sufficient information to deduce the sensing mechanisms. Finally, the Cu NCs showed high biocompatibility and were able to be used for fluorescence bioimaging in living cells. This study provided a novel and simple strategy to construct the multifunctional chemosensors for bioanalytical applications.

show abstract