Determination of optimal extraction conditions for phenolic compounds from Pistacia atlantica leaves using the response surface methodology

Ahmed, Ziyad Ben; Yousfi, Mohamed; Viaene, Johan; Dejaegher, Bieke; Demeyer, Kristiaan; Mangelings, Debby; Heyden, Yvan Vander

doi:10.1039/c6ay01739h

Cited by 42 publications

(20 citation statements)

References 22 publications

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“…However, applying temperature higher than 308 K decreases the TPC. These results are in good agreement with other previous researches that related the decreasing of TPC to the decomposition of phenolic compounds when they reach a higher critical temperature [23]. This critical ultrasound temperature can cleave chemical bounds between atoms and facilitate the destruction of phenolic molecules [22].…”

Section: Determination Of the Experimental Ranges Of Independent Varisupporting

confidence: 93%

Microcrystalline Cellulose from Groundnut Shell as Potential Adsorbent of Crystal Violet and Methylene Blue. Kinetics, Isotherms and Thermodynamic Studies

Zango¹,

Imam²

2020

ChChT

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Section: Determination Of the Experimental Ranges Of Independent Varisupporting

confidence: 93%

Microcrystalline Cellulose from Groundnut Shell as Potential Adsorbent of Crystal Violet and Methylene Blue. Kinetics, Isotherms and Thermodynamic Studies

Zango¹,

Imam²

2020

ChChT

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“…The P values are used to determine the significance of the model: the lower the P values, the higher is the model significance. Moreover, P < 0.05 indicates a significant model 28 . Thus, this model was highly significant because it showed p < 0.0001.…”

Section: Resultsmentioning

confidence: 92%

“…Moreover, P < 0.05 indicates a significant model. 28 Thus, this model was highly significant because it showed p < 0.0001.…”

Section: Optimization Of Ua-sle Process and Statistical Analysismentioning

confidence: 89%

Application of response surface methodology for optimization of ultrasound‐assisted solid‐liquid extraction of phenolic compounds from Cenostigma macrophyllum

Moreira

Filho

Carvalho

et al. 2020

Journal of Chemometrics

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This study determines the optimal conditions for the ultrasound-assisted solidliquid extraction (UA-SLE) of the total phenolic compounds (TPC) of Cenostigma macrophyllum leaves. The experiments were carried out according to three-level, four-variable Box-Behnken design combined with the response surface methodology (RSM). Extraction (sonication) time, liquid-solid ratio, methanol concentration, and ultrasonic power were investigated as independent variables to obtain the optimal extraction conditions for TPC. Data were fitted to a second-order polynomial model, and the model fitness was evaluated by the analysis of variance, which indicated the model (P < 0.0001), presenting precision and reliability with the experiments performed (R 2 = 0.9947, coefficient of variance [CV] = 4.29, SD = 1.67). Individual and interactive effects of the independent variables on TPC extraction were interpreted using the proposed mathematical model. The results showed that for the maximum TPC extraction, the optimal conditions included 32 min extraction time, 29.73 mLÁg −1 liquid-solid ratio, 47.72% methanol concentration, and 145.71 W ultrasonic power. Under these optimal conditions, the predicted values were in agreement with the experimental values, thus validating the RSM model. When the optimal conditions were compared with those of conventional extraction techniques, the results showed that UA-SLE presented significantly better results for TPC extraction (71.2% to 138.3% more efficient) and for antioxidant activity (115.0% to 179.2% more efficient). High-performance liquid chromatography analysis of the extracts revealed that UA-SLE did not interfere with the extract chemical composition, thus confirming that it was more effective than conventional techniques.

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“…Ferric-reducing antioxidant power (FRAP) is defined as plasma ability to reduce iron complexes and reflects plasma antioxidant potential [36].…”

Section: Ferric-reducing Antioxidant Powermentioning

confidence: 99%

Is the Oxidative Stress in Obstructive Sleep Apnea Associated with Cardiovascular Complications?—Systematic Review

Fiedorczuk

Stróżyński

Olszewska

2020

JCM

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Obstructive sleep apnea (OSA) is a prevalent, underdiagnosed disease and is considered an independent risk factor for cardiovascular disease. The exact mechanism of cardiovascular complications (CVC) development as a complication of OSA is not entirely understood. Oxidative stress is suspected to be the essential factor in initiating various comorbidities in OSA. Biomarkers of nonenzymatic lipid and protein peroxidation, DNA repair and antioxidant capabilities measured in serum, plasma and urine are frequently used to assess the presence of oxidative stress. We conducted a systematic review and quality assessment of available observational analytic studies to determine whether there is an association between oxidative stress and OSA in patients with prevalent CV disease compared to (a) patients with prevalent CV disease but no OSA, (b) patients with prevalent CV disease and less severe OSA and (c) patients with OSA and no overt CV disease. This systematic review demonstrated that, while oxidative stress is associated with OSA, there was no clear difference in the severity of oxidative stress between OSA patients with or without cardiovascular complications.

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Determination of optimal extraction conditions for phenolic compounds from Pistacia atlantica leaves using the response surface methodology

Abstract: Response surface methodology in combination with a Box–Behnken design was performed to optimize the extraction conditions, resulting in a maximum total phenolic content yield from Pistacia atlantica leaves.

Cited by 42 publications

References 22 publications

Microcrystalline Cellulose from Groundnut Shell as Potential Adsorbent of Crystal Violet and Methylene Blue. Kinetics, Isotherms and Thermodynamic Studies

Microcrystalline Cellulose from Groundnut Shell as Potential Adsorbent of Crystal Violet and Methylene Blue. Kinetics, Isotherms and Thermodynamic Studies

Application of response surface methodology for optimization of ultrasound‐assisted solid‐liquid extraction of phenolic compounds from Cenostigma macrophyllum

Is the Oxidative Stress in Obstructive Sleep Apnea Associated with Cardiovascular Complications?—Systematic Review

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