Determination of oxeladin in human sera by gas—liquid chromatography with thermionic detection

Salvesen, Bjarne; Haugland, Torleif

doi:10.1016/s0378-4347(00)80297-2

Cited by 11 publications

(6 citation statements)

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“…Determination of oxeladine in human sera by gas-liquid chromatography with thermionic detection was carried out [23]. This paper describes a gas-liquid chromatographic (GLC) method developed for the determination of oxeladine in serum samples in bioavailability tests of oxeladine from tablet and linctus formulations.…”

Section: Pharmacological Actionmentioning

confidence: 99%

Review Article: Instrumental Analysis of Olopatadine Hydrochloride, Oxeladine Citrate, Amlodipine Besylate and Xipamide

M¹,

E²,

M³

et al. 2020

Int J Analyt Bioanalyt Methods

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In this literature review, we will introduce all reported methods that have been developed for determination of the antihistaminic drug, olopatadine HCl, the cough suppressant drug oxeladine citrate, and certain antihypertensive drugs such as amlodipine besylate and xipamide in their pure form, combined form with other drugs, combined form with degradation products, and in biological samples. We also will shed the light on the most important combination of drugs that are used for treatment of allergy and hypertension.

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Section: Pharmacological Actionmentioning

confidence: 99%

Review Article: Instrumental Analysis of Olopatadine Hydrochloride, Oxeladine Citrate, Amlodipine Besylate and Xipamide

M¹,

E²,

M³

et al. 2020

Int J Analyt Bioanalyt Methods

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“…Plasma samples were alkalinized and extracted using hexane:isoamyl alcohol. Determination of oxeladine in human sera by gas-liquid chromatography with thermionic detection was carried out [23]. This paper describes a gas-liquid chromatographic (GLC) method developed for the determination of oxeladine in serum samples in bioavailability tests of oxeladine from tablet and linctus formulations.…”

Section: Pharmacological Actionmentioning

confidence: 99%

Review Article: Instrumental Analysis of Olopatadine Hydrochloride, Oxeladine Citrate, Amlodipine Besylate and Xipamide

M¹,

E²,

M³

et al. 2020

Int J Analyt Bioanalyt Methods

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“…Olopatadine is official in Indian Pharmacopeia [2] and United state Pharmacopeia [3]. From the literature review, it is observed that many analytical methods have been developed involving spectrophotometric [4][5][6][7][8][9][10][11][12][13][14], LC [14], HPLC [12,[15][16][17], Volttametry [20], HPTLC [15,[18][19], stability-indicating HPLC method [17] and LC-ESI-MS/MS [21] for the estimation of OLO in pharmaceutical formulations. Mometasone furoate (MOM) Figure 2 F I G U R E 2 Structure of Mometasone Furoate.…”

Section: Introductionmentioning

confidence: 99%

“…Olopatadine is official in Indian Pharmacopeia [2] and United state Pharmacopeia [3]. From the literature review, it is observed that many analytical methods have been developed involving spectrophotometric[4–14], LC [14], HPLC [12, 15–17], Volttametry [20], HPTLC [15, 18–19], stability‐indicating HPLC method [17] and LC‐ESI‐MS/MS [21] for the estimation of OLO in pharmaceutical formulations. Mometasone furoate (MOM) Figure 2, chemically [(8 S ,9 R ,10 S ,11 S ,13 S ,14 S ,16 R ,17 R )−9‐chloro‐17‐(2‐chloroacetyl)−11‐hydroxy‐10,13,16‐trimethyl‐3‐oxo‐6,7,8,11,12,14,15,16‐octahydrocyclopenta[a]phenanthren‐17‐yl] furan‐2‐carboxylate Topical glucocorticoid receptor (GR) agonist with dermatological properties.…”

Section: Introductionmentioning

confidence: 99%

A specific high‐performance thin‐layer chromatography method validated for estimation of mometasone furoate and olopatadine hydrochloride

Patel

2023

Separation Science Plus

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High‐performance thin‐layer chromatography has the capacity to run many samples simultaneously and reduced solvent usage, It offers a number of advantages that can save both time and money. The simultaneous quantification of mometasone furoate and olopatadine hydrochloride in a combined dose has been developed and validated using a specific, precise, accurate, and economical high‐performance thin‐layer chromatography technique. Methanol: Water (8: 2, v/v) was used as the mobile phase during the separation, which took place on a stationary phase of pre‐coated silica gel aluminum plate 60 F254. At 248 nm, separated components were densitometrically measured. The method was validated for Linearity and range, precision, reproducibility, specificity, accuracy, the limit of detection, and the limit of quantification as per the International Council for Harmonization Q2(R1) guideline. mometasone furoate and olopatadine hydrochloride regression coefficients (R2) were found to be 0.9995 and 0.9991, accordingly. Mometasone furoate and olopatadine hydrochloride percentage recoveries were measured to be 98.99 ± 0.39 and 99.15 ± 0.95, respectively. The analytical findings demonstrate that the proposed approach could be used to quantify mometasone furoate and olopatadine HCl simultaneously in a combined dose.

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Determination of oxeladin in human sera by gas—liquid chromatography with thermionic detection

Cited by 11 publications

References 1 publication

Review Article: Instrumental Analysis of Olopatadine Hydrochloride, Oxeladine Citrate, Amlodipine Besylate and Xipamide

Review Article: Instrumental Analysis of Olopatadine Hydrochloride, Oxeladine Citrate, Amlodipine Besylate and Xipamide

Review Article: Instrumental Analysis of Olopatadine Hydrochloride, Oxeladine Citrate, Amlodipine Besylate and Xipamide

A specific high‐performance thin‐layer chromatography method validated for estimation of mometasone furoate and olopatadine hydrochloride

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