Determination of phthalate esters in cleaning and personal care products by dispersive liquid–liquid microextraction and liquid chromatography–tandem mass spectrometry

Viñas, Pilar; Campillo, Natalia; Pastor-Belda, Marta; Oller, Ainhoa; Hernández‐Córdoba, Manuel

doi:10.1016/j.chroma.2014.12.012

Cited by 72 publications

(33 citation statements)

References 33 publications

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“…Dispersive liquid-liquid microextraction (DLLME; Viñas et al 2015a;Farajzadeh et al 2015) was developed to reduce the extraction time and enhance enrichment factors by injecting extraction solvents and disperser solvents into aqueous sample to form cloudy state. However, the extraction solvents are usually chlorobenzene, chloroform, and carbon tetrachloride; all of them are very toxic and environmentally hazardous (Viñas et al 2014a).…”

Section: Introductionmentioning

confidence: 99%

Determination of Sudan Dyes in Juice Samples via Solidification of Ionic Liquid in Microwave-Assisted Liquid-Liquid Microextraction Followed by High-Performance Liquid Chromatography

Song

et al. 2016

Food Anal. Methods

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Solidification of ionic liquid (SIL) has been applied in microwave-assisted liquid-liquid microextraction method for analyzing Sudan dyes in juice samples. 1-Ethy-3-methylimidazolium hexafluorophosphate ([C 2 MIM][PF 6 ]) was selected as the extraction solvent due to its relatively high melting point. With the aid of microwave irradiation, the dyes could be easily extracted into ionic liquid phase without dispersive solvent. The solid microdroplet could be easily separated from liquid. Compared with traditional dispersive liquidliquid microextraction, this method will greatly simplify the collection procedure and shorten the operation time. Several experimental parameters, including the amount of ionic liquid, microwave power and irradiation time, pH of sample solution, and ionic strength, were systematically investigated and optimized. The limits of detection for Sudan I, II, III, and IV were 1.08, 1.30, 1.14, and 1.19 μg/L, respectively. The recoveries of the analytes ranged from 83.42 to 115.56 % and relative standard deviations were lower than 11.53 %, when the present method was applied to the analysis of real samples.

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Section: Introductionmentioning

confidence: 99%

Determination of Sudan Dyes in Juice Samples via Solidification of Ionic Liquid in Microwave-Assisted Liquid-Liquid Microextraction Followed by High-Performance Liquid Chromatography

Song

et al. 2016

Food Anal. Methods

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“…Of the classes of chemicals studied, we found that phthalate concentrations decreased the least, with a 27% average decrease in MEP, an 11% nonsignificant average decrease in MnBP, and no change in MiBP. The relatively modest change in these compounds over the intervention period may be attributable to the presence of these phthalates in other scented products in the home that were not replaced during the intervention, including air fresheners, fabric softeners, and cleaning products ( Buckley et al 2012 ; Cacho et al 2015 ; Viñas et al 2015 ) as well as ingestion of phthalates in food ( Colacino et al 2010 ) and medications ( Hernández-Díaz et al 2013 ; Kelley et al 2012 ). It is estimated that the majority of an adult woman’s cumulative exposure to DEP is through personal care product use, but that her cumulative exposure to DnBP and DiBP may also reflect significant uptake from food and house dust ( Guo and Kannan 2013 ).…”

Section: Discussionmentioning

confidence: 99%

Reducing Phthalate, Paraben, and Phenol Exposure from Personal Care Products in Adolescent Girls: Findings from the HERMOSA Intervention Study

Harley

Kogut

Madrigal

et al. 2016

Environ Health Perspect

171

125

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Background:Personal care products are a source of exposure to potentially endocrine-disrupting chemicals such as phthalates, parabens, triclosan, and benzophenone-3 (BP-3) for adolescent girls.Methods:We enrolled 100 Latina girls in a youth-led, community-based participatory research intervention study to determine whether using personal care products whose labels stated they did not contain these chemicals for 3 days could lower urinary concentrations. Pre- and postintervention urine samples were analyzed for phthalate metabolites, parabens, triclosan, and BP-3 using high-performance liquid chromatography/tandem mass spectrometry.Results:Urinary concentrations of mono-ethyl phthalate (MEP) decreased by 27.4% (95% CI: –39.3, –13.2) on average over the 3-day intervention; no significant changes were seen in urinary concentrations of mono-n-butyl phthalate (MnBP) and mono-isobutyl phthalate (MiBP). Methyl and propyl paraben concentrations decreased by 43.9% (95% CI: –61.3, –18.8) and 45.4% (95% CI: –63.7, –17.9), respectively. Unexpectedly, concentrations of ethyl and butyl paraben concentrations increased, although concentrations were low overall and not detected in almost half the samples. Triclosan concentrations decreased by 35.7% (95% CI: –53.3, –11.6), and BP-3 concentrations decreased by 36.0% (95% CI: –51.0, –16.4).Discussion:This study demonstrates that techniques available to consumers, such as choosing personal care products that are labeled to be free of phthalates, parabens, triclosan, and BP-3, can reduce personal exposure to possible endocrine-disrupting chemicals. Involving youth in the design and implementation of the study was key to recruitment, retention, compliance, and acceptability of the intervention.Citation:Harley KG, Kogut K, Madrigal DS, Cardenas M, Vera IA, Meza-Alfaro G, She J, Gavin Q, Zahedi R, Bradman A, Eskenazi B, Parra KL. 2016. Reducing phthalate, paraben, and phenol exposure from personal care products in adolescent girls: findings from the HERMOSA Intervention Study. Environ Health Perspect 124:1600–1607; http://dx.doi.org/10.1289/ehp.1510514

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“…LPME possesses high preconcentration factor and extraction efficiency, and can overcome the disadvantages of conventional LLE. Several configurations of LPME were used to determine a large number of active and nonallowed substances in different types of cosmetics [106][107][108][109][110][111][112][113][114][115][116][117].…”

Section: Lpme-based Techniquesmentioning

confidence: 99%

Current trends in sample preparation for cosmetic analysis

Zhong

2016

J of Separation Science

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The widespread applications of cosmetics in modern life make their analysis particularly important from a safety point of view. There is a wide variety of restricted ingredients and prohibited substances that primarily influence the safety of cosmetics. Sample preparation for cosmetic analysis is a crucial step as the complex matrices may seriously interfere with the determination of target analytes. In this review, some new developments (2010-2016) in sample preparation techniques for cosmetic analysis, including liquid-phase microextraction, solid-phase microextraction, matrix solid-phase dispersion, pressurized liquid extraction, cloud point extraction, ultrasound-assisted extraction, and microwave digestion, are presented. Furthermore, the research and progress in sample preparation techniques and their applications in the separation and purification of allowed ingredients and prohibited substances are reviewed.

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Determination of phthalate esters in cleaning and personal care products by dispersive liquid–liquid microextraction and liquid chromatography–tandem mass spectrometry

Cited by 72 publications

References 33 publications

Determination of Sudan Dyes in Juice Samples via Solidification of Ionic Liquid in Microwave-Assisted Liquid-Liquid Microextraction Followed by High-Performance Liquid Chromatography

Determination of Sudan Dyes in Juice Samples via Solidification of Ionic Liquid in Microwave-Assisted Liquid-Liquid Microextraction Followed by High-Performance Liquid Chromatography

Reducing Phthalate, Paraben, and Phenol Exposure from Personal Care Products in Adolescent Girls: Findings from the HERMOSA Intervention Study

Current trends in sample preparation for cosmetic analysis

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