Determination of phytochemical composition, cytotoxicity, genotoxicity and mutagenicity of the hydroethanolic extract of Dolichandra unguis-cati L. leaves in human leukocytes

Herbal medications were historically studied for possible uses as local anesthetics since they include natural bioactive components with analgesic and numbing characteristics. Plants such as Echinacea, Capsicum, Corydalis, and Clove have shown promising results in preclinical tests for their capacity to block nerve transmission and relieve pain when applied topically. These herbal medicines frequently interact with the neurological system, either by blocking nerve impulse transmission or by altering the ion channels involved in Pain perception. Herbal local anesthetics have gained popularity as alternatives to synthetic medications since they have been shown to be less harmful and have fewer adverse effects. While herbal medications have benefits, their efficacy, safety, and mechanism of action require additional clinical research to support their use in medical practice. This review investigates the pharmacological features of numerous herbal medicines with local anesthetic effects, highlighting their potential in pain management as well as the difficulties that remain for their clinical application. any herbal remedies contain anesthetic effects. Herbal medicines with local anesthetic qualities include clove, cinchona, datura, thymol, and spilanthes acmella, which are used in medicine and dentistry. However, their potential applications in dentistry have yet to be completely analyzed. Herbal medications have been widely used in traditional medicine for therapeutic purposes, specially as local anesthetics. This review will look at the numerous herbal compounds known for their local anesthetic properties, including their chemical compositions, methods of action, and clinical efficacy

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Determination of phytochemical composition, cytotoxicity, genotoxicity and mutagenicity of the hydroethanolic extract of Dolichandra unguis-cati L. leaves in human leukocytes

Cited by 3 publications

References 26 publications

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