“…Also, some analytical methods were reported for the determination of pirfenidone from the different matrix which includes pharmaceutical dosage forms and plasma. These are spectrophotometric (Thorat, Padmane, Tajne, & Ittadwar, 2016), spectrofluorometric (Sambhani & Biju, 2018), capillary electrophoresis (Sotgia et al, 2020), high-performance thin layer chromatography (Thorat et al, 2016), gas chromatography (Ma et al, 2017), and HPLC with an ultraviolet detector (Bodempudi, Babur, & Reddy, 2015;Parmar et al, 2014;Ravisankar, Anusha Rani, Devadasu, & Devala Rao, 2014;Thorat et al, 2016), a photodiode array detector (Bodempudi et al, 2015) and a mass spectrometry detector (Tong et al, 2010;Wen et al, 2014) methods.…”