Determination of plasma octopamine and its level in renal disease

Separation of octopamine racemate on (R,S)-2-amino-1-phenylethanol imprinted polymer – Experimental and computational studies

“…The functional monomers: methacrylic acid (2), trifluoromethacrylic acid (4), itaconic acid (5), isopropenylbenzene (7), 2-hydroxyethyl methacrylate (8), and 2-(diethylamino)ethyl methacrylate (9) were from Sigma-Aldrich (Steinheim, Germany), acrylamide (6) and allylamine (10) were from Fluka (Steinheim, Germany), 4-vinylbenzoic acid (1), acrylic acid (3) were from Alfa Aesar (Karlsruhe, Germany). The cross-linker, ethylene glycol dimethacrylate was purchased from Sigma-Aldrich (Steinheim, Germany).…”

“…A few analytical methods have been developed for its quantitative analysis including radioenzymatic assay [10], liquid chromatography [11] or capillary electrophoresis [12]. In the majority of cases the derivatization step is required to improve the sensitivity of methods.…”

Parlodel Treatment of Uremic Hypogonadism in Men

“…They might suggest inadequate hypothalamic regulation. The latter could be caused both by an effect of dopamine on LH-secretion (as shown in rats) [15] and a decrease in the dopamine level in uremia [12,13].…”

“…The concept is supported by evidence of neurotransmitter imbalance in the CNS in uremia (reduced dopamine content, elevated serotonine value and false neurotransmitter octopamine accumula tion) [12,13].…”

Plasma catecholamines in hepatic coma and liver cirrhosis: Role of octopamine

“…Normal mean values of octopamine have been found to be 0.40 ng/ml [5], 0.24 ng/ml with a range of 0 to 1.91 ng/ml [16], 1.6 ng/ml [31], 1.9 ng/ml [20] and 4.6 ng/ml [23]. However compared with the normal range of noradrenaline in plasma from 0.1 to 0.7 ng/ml the above mentioned normal levels of octopamine are unexpectedly high.…”