Determination of prebiotic utilisation capability of potential probiotic Bacillus velezensis FS26 through in silico and in vitro approaches

Sam-on, Muhamad Firdaus Syahmi; Mustafa, Shuhaimi; Hashim, Amalia Mohd; Yusof, Mohd Termizi; Zulkifly, Shahrizim; Roslan, Muhamad Akhmal Hakim

doi:10.1016/j.fbio.2023.102566

Cited by 2 publications

(1 citation statement)

References 53 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Prebiotics, such as fructo‐oligosaccharide (FOS), galacto‐oligosaccharide (GOS), and raffinose, are non‐digestible and could be utilised by probiotics and stimulate the growth and activities of probiotics in the colon, which are closely associated with their function (Krumbeck et al ., 2018; Tsai et al ., 2019). Study on the capability of probiotics to utilise prebiotics is an essential criterion for synergistic synbiotics preparation (Sam‐on et al ., 2023).…”

Section: Introductionmentioning

confidence: 99%

Combined effect of oligosaccharides combination on the growth of probiotics: synergistic or superposable?

Zhang,

Kang,

Han

et al. 2024

Int J of Food Sci Tech

View full text Add to dashboard Cite

SummarySynbiotics confer benefits to our health. Study on the promotion effects of prebiotics combinations on probiotics growth is necessary for synbiotics preparation. However, there exists few reports on how to combine different prebiotics. The aim of the study was to explore combined effect of prebiotics combinations in modulating probiotics growth for rational synbiotics development. Four prebiotic oligosaccharides were screened for their promotion effects on the growth of four representative probiotics. Then, SynergyFinder 3.0 was used for the first time to rationally analyse interaction of various oligosaccharides combinations. Results showed that there was no synergism between any of two oligosaccharides under the conditions studied, but rather a superposition effect. Finally, the optimal oligosaccharides combinations based on the maximum specific growth rate and the maximum cell yield were selected. This study advanced our knowledge of oligosaccharides utilisation by probiotics and provided guidance on the rational selection of oligosaccharides combinations for specific probiotics, which was important for the design of synergistic synbiotics.

show abstract

Section: Introductionmentioning

confidence: 99%