Sweet corn is popular in West Papua. This study was aimed at determining the production and chemical qualities of sweet corns using single fertilizer combination (SFC). A completely randomized design experiment was used with 5 treatments and 3 replications. The treatments were without fertilization (P0), with a concentration of P1 (22.4g/plant); P2 (23.52/plant); P3 (24.64g/plant); P4 (25.76g/plant). Variables observed were weight, length, diameter, pH, water, ash and fat content. The data obtained were analysed using analysis of variance continued with the Honest Significant Difference Test. Results showed that different concentrations gave a very significant difference (P<0.01) on cob weights (gr) (P0, P1, P2, P3, P4 were 51.39; 115.40; 133.06), cob lengths (mm) (78.45; 107.37; 113.92; 131.54;141.02), and cob diameters (mm) (24.56; 31.22; 34.29; 36.21; 37.55); did not give a significant difference (P>0.05) on pH (5.47; 5.37; 5.41; 5.40; 5.38), moisture content (%) (60.41; 60.75; 60.29; 60.08; 60.08), ash content (%) (1.95; 2.07; 2.05; 1.96; 1.92), and fat content (%) (0.62; 0.53; 0.43; 0.52; 0.40). The conclusion was that different concentrations of SFC did not give a different effect on pH, water, ash, fat content and gave a very significant difference effect on weight, length, diameter of sweet corn cobs.