Background:Silica is an element that accounts for 28 percent of the earth's crust. Silicosis is a relatively common cause of lung disease that is associated with high morbidity and mortality. Some types of work, such as mining, stone cutting, pottery, and road and building construction are associated with an increased risk of silica exposure, which can lead to silicosis. Silicosis is divided into acute, chronic, and accelerated forms. Due to the high prevalence and lack of proper treatment, use and detection of new trophy and particular prophylaxis methods against this disease is needed. Objectives: In addition, due to the side effects of drugs and the lack of their complete efficacy, we studied the effects of the natural compound, Chlorella vulgaris, in addition to the other available treatments. This study provided insight into the effectiveness of chlorella. Patients and Methods: Chlorella vulgaris was prescribed in addition to the other available chemical drugs for 8 weeks to a group of patients, and its effects on the clinical symptoms, general appearance, and spirometry indices were studied. Because increase confidence outcome of study the other group spot as control group. These two groups assimilate from all aspects. Results: This study showed that Algomed improves cough, sputum, dyspnea and lung auscultation findings. Therefore, the evaluation of spirometry indices showed improvement in FEV 1 and FVC. Conclusions: We conclude that Chlorella vulgaris is effective for treating silicosis. However, due to the limited number of patients and the short duration of the study, longer time periods and an increased number of patients are required for more definitive results.