Determination of reference values for tricuspid annular plane systolic excursion in healthy Turkish children

Abstract

Objective:Tricuspid annular plane systolic excursion (TAPSE) is an echocardiographic measurement used for evaluating right ventricular systolic function. While established reference values of TAPSE exist for the adult population, only a limited number of studies have attempted to evaluate reference values for the pediatric population. The aim of the present study was to determine the reference values for TAPSE in healthy children in Turkey.Methods:A total of 765 healthy children aged between 0 and 18 years, all of whom were referred to our clinic with cardiac murmurs, were evaluated prospectively. Patients with no cardiac pathologies or other disorders were excluded from the study. The measurement of TAPSE was obtained using a 2D-guided M-mode technique with echocardiography, and the relationship between age and surface area with TAPSE was investigated. The statistical analysis was carried out using the SPSS 20.0 software package (SPSS Inc., Chicago, IL, USA, 2012).Results:The mean TAPSE value was found to be 19.56±5.54 mm, and no significant difference was identified between male and female children. TAPSE values showed a positive correlation with increasing age and surface area. The mean TAPSE value was 9.09±1.36 mm in newborns and 25.91±3.60 mm in the 13-18 years age group. A negative correlation was seen between TAPSE and heart rate.Conclusion:In the present study, the reference values for TAPSE in healthy Turkish children were presented in percentile tables and the corresponding z-scores were determined. These reference values may be useful in daily practice for the evaluation of right ventricular systolic function in children.

Longitudinal Annular Systolic Displacement Compared to Global Strain in Normal Fetal Hearts and Those With Cardiac Abnormalities

“…Decreased annular displacement of the lateral walls of the RV and LVs has been suggested to be an indicator of cardiac dysfunction, which is unaffected by the ventricular preload and correlated with the ejection fraction in studies of children and adults . Previous studies of longitudinal displacement have focused primarily on evaluations of the lateral wall annulus using M‐mode US .…”

“…Decreased annular displacement of the lateral walls of the RV and LVs has been suggested to be an indicator of cardiac dysfunction, which is unaffected by the ventricular preload and correlated with the ejection fraction in studies of children and adults. 12,[50][51][52][53][54] Previous studies of longitudinal displacement have focused primarily on evaluations of the lateral wall annulus using M-mode US. 26,41,44,45,55 Although this approach provides important information regarding the contribution of the lateral and septal walls to ventricular contractility, it does not globally evaluate basal annular displacement.…”

Speckle Tracking of the Basal Lateral and Septal Wall Annular Plane Systolic Excursion of the Right and Left Ventricles of the Fetal Heart

“…Examination of longitudinal APSE has been demonstrated to be an indicator of cardiac dysfunction, unaffected by ventricular preload, and correlated with ejection fraction in studies of children and adults. 12,[24][25][26][27][28] For this reason, examination of the APSE from the right ventricular and left ventricular lateral and septal walls in the fetal heart may be an important tool for evaluation of basal-apical longitudinal contractility. Using the technique described in the current study identifies the endocardium abutting next to the annular insertion of the mitral and tricuspid valve leaflets (Figure 1).…”

Tricuspid annular plane systolic excursion and mitral annular plane systolic excursion cardiac reference values in 1300 healthy children: Single‐center results

“…Many studies have evaluated the use of TAPSE and MAPSE in adults; however, studies investigating TAPSE and MAPSE during childhood are scarce 3–10 . Children have shorter TAPSE and MAPSE values which are correlated positively both with age and body surface area (BSA).…”

“…Children have shorter TAPSE and MAPSE values which are correlated positively both with age and body surface area (BSA). Although TAPSE and MAPSE values are measured routinely in many clinics performing echocardiographic examination, few studies have so far reported their normal values in children 3–10 . In this study, we aimed to define reference ranges for TAPSE and MAPSE in a wide series of healthy children (n = 1300) aged 0‐18 years.…”