Determination of residual acrylamide monomer in solution and emulsion polymers by column-switching high-performance liquid chromatography

Tseng, Amy M.

doi:10.1016/0021-9673(90)85165-r

Cited by 3 publications

(1 citation statement)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The Wavelength for Detection. The UV wavelength range for AM detection reported by references [1,5,6] is from 200nm to 210nm. The UV scanning spectrum of AM solution from 200nm to 300nm (Figure 3) shows that the absorption peak is strong from 205nm to 230nm.…”

Section: Resultsmentioning

confidence: 99%

Determination of Residual Acrylamide Monomer in Medical Polyacrylamide Hydrogel by HPLC-SPE

Wan

Zhao

et al. 2005

KEM

View full text Add to dashboard Cite

The polyacrylamide hydrogel (PAMG) has been used in cosmetology in China, Ukraine and Russia since 1990s. Because the monomer acrylamide(AM) used to produce PAMG has been implicated as a potential mutagen and reproductive toxicant[1,2], it is important to accurately determine the amount of residual AM monomer in the PAMG. In this study, a quick, practical and simple method to determine AM is presented with respect to the hydrogel. AM is analysed quantitatively by ODS-3 column with ultraviolet (UV) absorbance detector. AM is separated from interferential component with an aqueous solution of 0.9%NaCl (NS) adjusted at pH~3.7 using hydrochloric acid and then detected at a UV wavelength of 210 nm. The results show that ODS-3 is effective approach for quantifying AM concentrations in PAMG. This method has a lower detection limit of 0.003µg/ml and a linear response range of 0.003 and 0.9 µg/ml (depending on the range required for analysis). Precision studies give coefficients of variation of <3.2%(n=5) for 0.003µg/ml. The recoveries for this method are greater than 90%. When AM content in PAMG is lower than the detection limit of this method, SPE (solid phase extraction) could be used to concentrate AM. In the case, C18 cartridge is used. And the recoveries are about 70% for SPE when AM concentration is lower than ppb.

show abstract

Section: Resultsmentioning

confidence: 99%

Determination of Residual Acrylamide Monomer in Medical Polyacrylamide Hydrogel by HPLC-SPE

Wan

Zhao

et al. 2005

KEM

View full text Add to dashboard Cite

show abstract

Alternative extraction techniques for analysis of acrylamide in food: Influence of pH and digestive enzymes

Eriksson

Karlsson

2006

LWT - Food Science and Technology

View full text Add to dashboard Cite

Determination of Acrylamide Monomer in Polyacrylamide Degradation Studies by High-Performance Liquid Chromatography

Vers¹

1999

Journal of Chromatographic Science

View full text Add to dashboard Cite

A high-performance liquid chromatography method using C18 and ion-exchange columns in series is developed for the determination of acrylamide and acrylic acid monomers in polymeric samples. The C18 column acts as a guard column, trapping surfactants and impurities and retaining the nonionic species. The ion-exchange column then separates the monomers according to their respective ionic strengths. This method has been proven in the laboratory to work successfully for all types of acrylamide/acrylic acid polymers and matrices. Detection limits for both monomers can be achieved in the parts-per-billion range. The method is used to study the possible degradation of polyacrylamide to acrylamide monomer in the presence of glyphosate (a herbicide) and sunlight. Polyacrylamide is used as a spray drift reduction aid in combination with glyphosate. In normal applications, the polymer and herbicide are in contact with each other in the presence of sunlight. The results show that the polymer does not degrade to acrylamide in the presence of glyphosate or sunlight or any combination of the two. It is also observed that glyphosate influences the solubility of polyacrylamide, and care must be used when combining the two.

show abstract

Determination of residual acrylamide monomer in solution and emulsion polymers by column-switching high-performance liquid chromatography

Cited by 3 publications

References 14 publications

Determination of Residual Acrylamide Monomer in Medical Polyacrylamide Hydrogel by HPLC-SPE

Determination of Residual Acrylamide Monomer in Medical Polyacrylamide Hydrogel by HPLC-SPE

Alternative extraction techniques for analysis of acrylamide in food: Influence of pH and digestive enzymes

Determination of Acrylamide Monomer in Polyacrylamide Degradation Studies by High-Performance Liquid Chromatography

Contact Info

Product

Resources

About