Determination of rubella virus-specific humoral and cell-mediated immunity in pregnant women with negative or equivocal rubella-specific IgG in routine screening

Picone, Olivier; Bouthry, Elise; Bejaoui-Olhmann, Y; Cordier, Anne-Gaël; Nédellec, Steven; Letourneau, Alexandra; Carbonel, M; Brollo, Marion; Grangeot-Keros, L.; Ayoubi, Jean-Marc; Benachi, Alexandra; Rouge, E; Vauloup‐Fellous, Christelle

doi:10.1016/j.jcv.2019.01.009

Cited by 12 publications

(5 citation statements)

References 41 publications

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“…Should they receive one or more MMR booster doses? Picone et al [115] have shown that even those who are determined to be rubella antibody negative can be antibody positive by other methods or show a secondary immune response to revaccination. On the other hand, the literature includes reports of measles in fully vaccinated HCWs [116] , [117] , [118] , [119] , so theoretically it may also be possible considering rubella.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and management of rubella susceptibility in healthcare workers in Italy: A systematic review and meta-analysis

et al. 2022

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Section: Discussionmentioning

confidence: 99%

Prevalence and management of rubella susceptibility in healthcare workers in Italy: A systematic review and meta-analysis

et al. 2022

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“…This may be a result of the composition of the RUBI-1-94 international standard, which is not a pure analyte but a composite of pooled human immunoglobulin (Dimech et al, 2016). Third, studies in vaccinated populations have reported that lower titres than the international standard for seronegative titres of 10 IU/ ml may still be protective in vaccinated individuals (Bouthry et al, 2016;Picone et al, 2019). In the present study, cut-off values of <8 IU/ ml as seronegative and !11 IU/ml as seropositive were applied, as recommended by the manufacturer (Euroimmun).…”

Section: Discussionmentioning

confidence: 60%

Rubella seroprevalence in pregnant women living with and without HIV in Soweto, South Africa

Gieles

Mutsaerts

Kwatra

et al. 2020

International Journal of Infectious Diseases

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Rubella infection during pregnancy may cause foetal death or congenital rubella syndrome. In South Africa, the national public immunization programme does not include rubella vaccination. The aim of this study was to evaluate rubella sero-epidemiology in pregnant South African women living with and without HIV. Methods: Serum samples obtained from women living with HIV (n = 552) and without HIV (n = 552) were tested for rubella immunoglobulin G antibodies using an ELISA. The proportions of women with seronegative titres (<8 IU/ml) and seropositive titres (!11 IU/ml), and geometric mean titres (GMT) were compared by age group and HIV status. Results: The overall proportion of rubella seropositivity was 97.8%. The proportion of seropositive women increased with age group (18-25 years: 97.0%; 26-32 years: 97.7%; 33-40 years: 99.3%; p = 0.047 after adjusting for HIV status). Similar proportions of women living with and without HIV were seropositive. Conclusions: Rubella immunity was high among South African pregnant women living with and without HIV in the absence of rubella vaccination in the public immunization programme. However, a lower percentage of younger women had seropositive titres, indicating the need for routine rubella vaccination after an increase in vaccine coverage rates.

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“…Serological monitoring of rubella susceptibility in women attending Obstetrics and Gynecology clinic can be used to monitor the performance of rubella immunization services. If serological screening is conducted, arrangements should be made to provide postpartum rubella vaccination to women found to be seronegative 21 .…”

Section: Resultsmentioning

confidence: 99%

Rubella immunity in a cohort of pregnant women – serological survey

Karcheva¹,

Petrov²,

Blazhev³

2019

Arch Balk Med Union

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Immunité contre le virus de la rubéole chez un groupe de femmes enceintes-étude sérologique Introduction. La rubéole est une maladie contagieuse à l'échelle mondiale aux symptômes légers et une éruption cutanée généralisée. L'épidémiologie de la rubéole a changé après l'autorisation du vaccin en 1969. La rubéole chez les enfants représente une infection spontanément résoluble, mais lors d'une grossesse le foetus risque d'être gravement atteint. Objectifs. Le but de cette recherche est d'évaluer l'immunité contre le virus de la rubéole chez les femmes enceintes dans la région de Pleven, Bulgarie. Méthodes. Une recherche transversale a été conduite incluant des femmes enceintes hospitalisées au Département d'obstétrique-gynécologie de l'Hôpital Universitaire de Pleven, Bulgarie. Une détermination quantitative des anticorps Immunoglobuline G (IgG) spécifiques contre le virus de la rubéole a été menée à l'aide de la méthode immuno-enzymatique ELISA. Le logiciel Microsoft Office Excel 2007 a été utilisé pour analyser les données.

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Determination of rubella virus-specific humoral and cell-mediated immunity in pregnant women with negative or equivocal rubella-specific IgG in routine screening

Cited by 12 publications

References 41 publications

Prevalence and management of rubella susceptibility in healthcare workers in Italy: A systematic review and meta-analysis

Prevalence and management of rubella susceptibility in healthcare workers in Italy: A systematic review and meta-analysis

Rubella seroprevalence in pregnant women living with and without HIV in Soweto, South Africa

Rubella immunity in a cohort of pregnant women – serological survey

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