Determination of serum visfatin levels in patients with Behçet’s disease: A case–control study

Shenavandeh, Saeedeh; Barkhordar, Maryam; Sarvestani, Eskandar Kamali; Aflaki, Elham; Agahi, Zahra Habib; Nazarinia, Mohammad Ali

doi:10.1016/j.ejr.2014.12.004

Cited by 1 publication

(1 citation statement)

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“…Several markers and mechanisms have been involved in the pathogenesis of BD and development of vascuitis including oxidative stress [2], apoptosis [3,4], cytokine and adipocytokine overproduction [5][6][7], vascular endothelial growth factors [8,9] and gene polymorphism [10]. Vasculitis and endothelial dysfunction are believed to be the pathogenic mechanism of a part but not the whole of the clinical spectrum of the disease [11].…”

Section: Introductionmentioning

confidence: 99%

Assessment of left ventricular function and aortic elastic properties in patients with Behçet’s disease using conventional and tissue Doppler echocardiography

Hassan

Ebaid

2016

The Egyptian Rheumatologist

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Background: Behc¸et disease (BD) is a multisystemic, chronic inflammatory disorder of unknown etiology with diffuse clinical manifestations including the cardiovascular system.Aim of the work: To assess left ventricular (LV) function and thoracic aorta elastic properties in BD patients using Doppler echocardiography and to correlate echocardiographic findings with disease activity.Patients and methods: The LV functions and thoracic aorta elastic properties were assessed in 30 BD patients and 30 controls using conventional and Tissue Doppler Imaging (TDI) echocardiography. Disease activity was evaluated using Behc¸et's disease current activity form (BDCAF). Erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), cholesterol and triglyceride levels were measured.Results: In BD patients, ESR and CRP were significantly elevated while cholesterol and triglycerides were comparable to the levels in the control. In conventional echocardiography, BD patients had significantly higher aortic diastolic diameter (p < 0.05), aortic stiffness index (p < 0.001), isovolumic relaxation time (p < 0.001), flow propagation velocity (FPV) and peak E-wave velocity/FPV (E/FPV) (p < 0.001) than the control group while aortic strain was significantly lower

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