Determination of sisomicin, netilmicin, astromicin and micronomicin in serum by high-performance liquid chromatography

Kawamoto, Tomoaki; Mashimo, Ikuo; Yamauchi, Shigeki; Watanabe, Makoto M.

doi:10.1016/s0378-4347(00)83351-4

Cited by 25 publications

(12 citation statements)

References 5 publications

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“…Several methods have been described to determine netilmicin in pharmaceutical formulations and biological matrices. Precolumn derivatization LC with dansyl chloride 10, o ‐phthalaldehyde (OPA) 11–14, 1‐fluoro‐2,4‐dinitrobenzene 15, 16, 11‐fluorenylmethyl chloroformate 17, or OPA‐β‐mercaptopropionic acid 18, 19, and postcolumn LC derivatization with OPA 20, 21 combined with fluorescence or UV detection have been described. However, these techniques are time consuming and give problems in quantification.…”

Section: Introductionmentioning

confidence: 99%

Role of Water in the Chlorine Evolution Reaction at RuO₂‐Based Electrodes—Understanding Electrocatalysis as a Resonance Phenomenon

et al. 2012

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The reaction path of the Cl(2) evolution reaction (CER) was investigated by combining electrochemical and spectroscopic methods. It is shown that oxidation and reconstruction of the catalyst surface during CER is a consequence of the interaction between RuO(2) and water. The state of the RuO(2) surface during the electrochemical reaction was analyzed in situ by using Raman spectroscopy to monitor vibrations of the crystal lattice of RuO(2) and changes in the surface concentration of the adsorbed species as a function of the electrode potential. The role of the solvent was recognized as being crucial in the formation of an oxygen-containing hydrophilic layer, which is a key prerequisite for electrocatalytic Cl(2) formation. Water (more precisely the OH adlayer) is understood not just as a medium that allows adsorption of intermediates, but also as an integral part of the intermediate formed during the electrochemical reaction. New insights into the general understanding of electrocatalysis were obtained by utilizing the vibration frequencies of the crystal lattice as a dynamic catalytic descriptor instead of thermodynamic descriptors, such as the adsorption energy of intermediates. Interpretation of the derived "volcano" curve suggests that electrocatalysis is governed by a resonance phenomenon.

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Section: Introductionmentioning

confidence: 99%

Role of Water in the Chlorine Evolution Reaction at RuO₂‐Based Electrodes—Understanding Electrocatalysis as a Resonance Phenomenon

et al. 2012

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“…Several methods have been described to determine netilmicin in pharmaceutical formulations and biological matrices. Precolumn derivatization LC with dansyl chloride [10], o-phthalaldehyde (OPA) [11][12][13][14], 1-fluoro-2,4-dinitrobenzene [15,16], 11-fluorenylmethyl chloroformate [17], or OPA-b-mercaptopropionic acid [18,19], and postcolumn LC derivatization with OPA [20,21] combined with fluorescence or UV detection have been described. However, these techniques are time consuming and give problems in quantification.…”

Section: Introductionmentioning

confidence: 99%

Development and validation of an improved reversed‐phase liquid chromatographic method combined with pulsed electrochemical detection for the analysis of netilmicin

Manyanga

Hoogmartens

Adams

2010

J of Separation Science

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Netilmicin is one of the aminoglycoside antibiotics that lacks a strong UV absorbing chromophore. However, the application of pulsed electrochemical detection has been used successfully for the direct analysis of aminoglycoside antibiotics. This study describes an improved LC method combined with pulsed electrochemical detection for the analysis of netilmicin. Using a Zorbax SB C-18 column (250 mm x 4.6 mm id, 5 microm), isocratic elution was carried out with a mobile phase containing sodium sulfate (20 g/L), sodium octanesulfonate (0.3 g/L), THF (20 mL/L), and 0.2 M phosphate buffer pH 3.0 (50.0 mL/L). The robustness of the method was examined by means of an experimental design. The method proved to be sensitive, repeatable, linear, and robust. The method has also been used to analyze some commercial netilmicin samples.

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“…The traditional high-performance liquid chromatography (HPLC) methods measure Siso after derivatizing the free amino group with fluorescent reagents [2][3][4][5][6][7][8]. It is necessary to purify the samples after extraction in most detection methods.…”

Section: Introductionmentioning

confidence: 99%

Development of a non-derivatization high-performance liquid chromatography method with resonance Rayleigh scattering detection for the detection of sisomicin in rat serum

Zhang

Liu

et al. 2009

Journal of Chromatography B

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Determination of sisomicin, netilmicin, astromicin and micronomicin in serum by high-performance liquid chromatography

Cited by 25 publications

References 5 publications

Role of Water in the Chlorine Evolution Reaction at RuO₂‐Based Electrodes—Understanding Electrocatalysis as a Resonance Phenomenon

Role of Water in the Chlorine Evolution Reaction at RuO₂‐Based Electrodes—Understanding Electrocatalysis as a Resonance Phenomenon

Development and validation of an improved reversed‐phase liquid chromatographic method combined with pulsed electrochemical detection for the analysis of netilmicin

Development of a non-derivatization high-performance liquid chromatography method with resonance Rayleigh scattering detection for the detection of sisomicin in rat serum

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Determination of sisomicin, netilmicin, astromicin and micronomicin in serum by high-performance liquid chromatography

Cited by 25 publications

References 5 publications

Role of Water in the Chlorine Evolution Reaction at RuO2‐Based Electrodes—Understanding Electrocatalysis as a Resonance Phenomenon

Role of Water in the Chlorine Evolution Reaction at RuO2‐Based Electrodes—Understanding Electrocatalysis as a Resonance Phenomenon

Development and validation of an improved reversed‐phase liquid chromatographic method combined with pulsed electrochemical detection for the analysis of netilmicin

Development of a non-derivatization high-performance liquid chromatography method with resonance Rayleigh scattering detection for the detection of sisomicin in rat serum

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Role of Water in the Chlorine Evolution Reaction at RuO₂‐Based Electrodes—Understanding Electrocatalysis as a Resonance Phenomenon

Role of Water in the Chlorine Evolution Reaction at RuO₂‐Based Electrodes—Understanding Electrocatalysis as a Resonance Phenomenon