Determination of the activity meter calibration factor for Rhenium-188

Introduction: During the development of novel Re-188 radiopharmaceuticals, it was discovered that no calibration settings were published to calibrate Re-188 on the Capintec CRC25PET dose calibrator. Methods: Thus, an elution of sodium [188Re]perrhenate from an OncoBeta 188W/188Re generator was used to measure activity on a Capintec CRC-25R dose calibrator using established dose calibrator settings provided by the manufacturer. Results: Thereafter, the same [188Re]perrhenate solution was used to tune the calibration settings on a Capintec CRC-25PET dose calibrator, accounting for geometry, and thus determine the previously unreported calibration number for measuring Re-188 labelled research samples. Conclusion: Breakthrough of <0.01% W-188 was verified via gamma spectroscopy to ensure radionuclidic purity of the [188Re]perrhenate source used for calibration.

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Determination of the Re-188 Calibration Number for the Capintec CRC- 25PET Dose Calibrator

Klenner

Poole

2023

CRP

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Determination of the activity meter calibration factor for Rhenium-188

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References 7 publications

Determination of the Re-188 Calibration Number for the Capintec CRC- 25PET Dose Calibrator

Determination of the Re-188 Calibration Number for the Capintec CRC- 25PET Dose Calibrator

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