Determination of the Cadmium, Chromium, Nickel, and Lead Ions Relays in Selected Polish Medicinal Plants and Their Infusion

Mirosławski, J; Paukszto, A.

doi:10.1007/s12011-017-1072-5

Cited by 29 publications

(17 citation statements)

References 13 publications

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“…The results obtained in this study, concerning lead contamination of samples of herbs and spices, correspond with earlier studies on this subject matter, conducted in Poland. Mirosławski and Pakuszto [ 26 ] analysed herbs (leaf of peppermint and flower of camomile) available on the Polish market and noted average levels of lead in the range of 0.440 mg/kg–1.110 mg/kg. Similar results concerning the levels of Pb in selected Polish herbs and spices (green matter of basil, root of curcuma, flower buds of clove tree, fruits of black pepper and peppers, onion, bear’s garlic, and allspice) were obtained by Krejpcio et al [ 27 ], who reported that the average content of lead varied in the range from 0.250 mg/kg to 1.490 mg/kg.…”

Section: Resultsmentioning

confidence: 99%

The Safety Assessment of Toxic Metals in Commonly Used Herbs, Spices, Tea, and Coffee in Poland

Kowalska

2021

IJERPH

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The presented study was aimed at the determination of the level of contamination with heavy metals (Cd, Pb, As, and Hg) in 240 samples of plant materials, i.e., herbal raw materials, spices, tea, and coffee. Moreover, a probabilistic risk assessment (noncarcinogenic and carcinogenic risks) was estimated by models including target hazard quotient (THQ) and cancer risk (CR). The samples were subjected to microwave mineralisation with the use of HNO3 (65%), while the determination of the content of the elements was performed with the use of inductively coupled plasma mass spectrometer (ICP–MS) and a mercury analyser. The element which was characterised by the highest level of accumulation in the analysed samples was lead (from 0.010 to 5.680 mg/kg). Among the heavy metals under analysis, the lowest concentration was noted in the case of mercury (from 0.005 to 0.030 mg/kg). A notably higher level of contamination with heavy metals was noted in the analysed samples of herbs and spices (0.005–5.680 mg/kg), compared to samples of tea and coffee (0.005–0.791 mg/kg). According to the guidelines of the World Health Organisation (WHO) concerning the limits of contamination of samples of herbal raw materials with heavy metals, lead levels exceeding the limits were only noted in 24 samples of herbs (18%). In all of the analysed samples of spices, tea, and coffee, no instances of exceeded limits were noted for any of the analysed heavy metals. The values of TTHQmax (in relation to the consumption of the analysed products) were as follows: up to 4.23 × 10−2 for spices, up to 2.51 × 10−1 for herbs, up to 4.03 × 10−2 for China tea, and up to 1.25 × 10−1 for roasted coffee beans. As the value of THQ ≤1, there is no probability of the appearance of undesirable effects related to the consumption of the analysed group of raw materials and products of plant origin. The CR value for As (max. value) was 1.29 × 10−5, which is lower than the maximum acceptable level of 1 × 10−4 suggested by United States Environmental Protection Agency (USEPA).

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Section: Resultsmentioning

confidence: 99%

The Safety Assessment of Toxic Metals in Commonly Used Herbs, Spices, Tea, and Coffee in Poland

Kowalska

2021

IJERPH

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“…Максимальные значения (0,72 мг/кг) зафиксированы для травы зверобоя и травы фиалки (Violae herba). Полученные результаты хорошо согласуются с российскими и иностранными данными литературы, согласно которым содержание кадмия в препаратах на основе индивидуальных растений редко превышает значение 0,8 мг/кг [21][22][23][24][25][26].…”

Section: Fig 2 Content Of Cadmium In the Herbal Medicinal Products unclassified

Comparative Analysis of Heavy Metal and Arsenic Content in Various Herbal Dosage Forms Marketed in Russia

Щукин¹,

Кузьмина²,

Shvetsova³

et al. 2020

Vedomosti Nauchnogo tsentra ekspertizy sredstv meditsinskogo pr

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The inclusion of requirements for independent determination of arsenic, cadmium, mercury, and lead, and the current sample preparation techniques into the State Pharmacopoeia of the Russian Federation (Ph. Rus.) requires the revision of the existing limits for elemental toxicants in herbal substances and herbal medicinal products produced from them.The aim of the study was to analyse the data on elemental toxicant content obtained during quality control of herbal substances (herbs, medicinal herb mixtures, extracts, and tinctures) using current test methods and sample preparation techniques, and to compare the obtained results with the Russian and foreign scientific and specialist literature.Materials and methods: the internal data on the content of critical heavy metals and arsenic in different dosage forms of herbal medicinal products, which were obtained by inductively coupled plasma mass spectrometry after sample preparation by decomposition in closed vessels, were compared with literature data. Results: it was demonstrated that the content of lead, cadmium, and mercury in all the test samples did not exceed the Ph. Rus. limits and was consistent with the analysed literature. The arsenic content in some herbal medicinal products was higher than the established Ph. Rus. limits, but complied with the less stringent Ph. Eur. and USP requirements for herbal substances. The authors investigated the link between the content of elemental toxicants and the place of collection and the part of the plant being tested. It was shown that different types of medicinal plants had a tendency to accumulate particular elements. The authors determined the content of the elements to be controlled in extracts and tinctures. The differences in the Russian and foreign requirements for the content of elemental toxicants may be attributed to the method of obtaining experimental data that form the basis for the setting of limits.Conclusions: the results of the study confirm the validity of the existing limits for elemental toxicants in herbal medicinal products. The authors demonstrated the need to revise the existing limits for arsenic in herbal medicinal products.

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“…Herbs and plants have been popularly used as oral medicine in many countries around the world because of their low cost and effectiveness (Dghaim et al, 2015;. Several studies have examined that toxic metals such as cadmium (Cd), arsenic (As) and lead (Pb), could be present in some herbs (Chizzola et al, 2003;Filipiak-Szok et al, 2015;Mirosławski & Paukszto, 2018;Queralt et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

Determining the content of toxic elements (Pb, Cd, and As) in herbal plants collected from different sites in northern Vietnam

Vuong¹

2020

J. Viet. Env.

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Plants might contain heavy metals from the surrounding polluted environment. Medicinal herb and plants, commonly used in Vietnam, may pose a risk to public health when polluted with heavy metals such as Pb, Cd and As. This study aims to investigate the content of Pb, Cd, and As in five selected herb plants (Phyllanthus urinaria L., Plantago asiatica L., Eleusine indica L., Wedelia chinensis (Osbeck) Merr, and Artemisia vulgaris L.). The samples were collected from natural sites in some provinces in northern Vietnam. The concentrations of Pb, Cd, and As were determined by the Inductively coupled plasma mass spectrometry (ICP-MS) method. The content of Pb, Cd and As was 0.247 ÷ 32.080 mg kg-1, 0.000 ÷ 1.099 mg kg-1, 0.000 ÷ 2.261 mg kg-1, respectively. A total of 50 out of the 58 investigated samples had concentrations of Pb, Cd, As lower than the permissible values of the World Health Organization (WHO). The remaining samples had contents of Pb or Cd or As significantly higher than the permissible limit defined by WHO. Thực vật có thể bị ô nhiễm do hấp thụ kim loại nặng từ môi trường ô nhiễm xung quanh. Các loại cây thảo dược được sử dụng phổ biến làm thuốc chữa bệnh ở Việt Nam. Chúng có thể gây nguy hiểm cho sức khỏe cộng đồng khi bị ô nhiễm kim loại nặng (Pb, Cd...vv.). Nghiên cứu này nhằm điều tra hàm lượng Pb, Cd và As trong năm loại cây thảo dược (cây Diệp Hạ Châu, cây Mã Đề, cây Cỏ Mần Trầu, cây Sài Đất và cây Ngải Cứu). Các mẫu cây này được lấy từ các địa điểm mọc tự nhiên ở một số tỉnh khác nhau thuộc khu vực miền bắc Việt Nam. Hàm lượng của Pb, Cd, và As được xác định bằng phương pháp ICP-MS. Hàm lượng Pb, Cd và As trong các mẫu phân tích lần lượt nằm trong khoảng là 0.247 ÷ 32.080 mg. Kg-1, 0.000 ÷ 1.099 mg. Kg-1, 0.000 ÷ 2.261 mg. Kg-1. 50 trên 58 mẫu phân tích có hàm lượng Pb, Cd, As thấp hơn giới hạn cho phép do tổ chức y tế thế giới (WHO) quy định. Có 8 trên 58 mẫu cây phân tích có hàm lượng Pb hoặc, Cd hoặc As cao hơn tiêu chuẩn giới hạn của WHO.

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Determination of the Cadmium, Chromium, Nickel, and Lead Ions Relays in Selected Polish Medicinal Plants and Their Infusion

Cited by 29 publications

References 13 publications

The Safety Assessment of Toxic Metals in Commonly Used Herbs, Spices, Tea, and Coffee in Poland

The Safety Assessment of Toxic Metals in Commonly Used Herbs, Spices, Tea, and Coffee in Poland

Comparative Analysis of Heavy Metal and Arsenic Content in Various Herbal Dosage Forms Marketed in Russia

Determining the content of toxic elements (Pb, Cd, and As) in herbal plants collected from different sites in northern Vietnam

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