Determination of the effect of green extraction solvents on the phenolic acids and flavonoids of propolis

Kekeçoğlu, Meral; Sorucu, Ali

doi:10.30782/jrvm.937418

Journal of Research in Veterinary Medicine

2022

DOI: 10.30782/jrvm.937418

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Determination of the effect of green extraction solvents on the phenolic acids and flavonoids of propolis

Meral Kekeçoğlu

Ali Sorucu

Abstract: The present study investigated the extraction of phenolic compounds from propolis according to solvent factor. The propolis samples were extracted in four different solvents, which water, ethanol-water (70%), dimethyl sulfoxide (DMSO), and L-lysine (8%), and were analyzed 36 phenolic compounds by HPLC-DAD. Statistically significant differences in solubility of the phenolic compound at various levels were detected among the solvents (P

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Cited by 3 publications

References 30 publications

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Electrochemical analysis and in silico molecular docking with tropomyosin-related kinase B reveals electron shuttles-mediated neuroprotective potential of mandarin orange pu-erh tea extracts

Ganzon,

Tsai,

Tayo

et al. 2025

Food Bioscience

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Electrochemical analysis and in silico molecular docking with tropomyosin-related kinase B reveals electron shuttles-mediated neuroprotective potential of mandarin orange pu-erh tea extracts

Ganzon,

Tsai,

Tayo

et al. 2025

Food Bioscience

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Phytochemical potential and GC–MS analysis of propolis from Punjab region of India

Barsola,

Saklani,

Kumari

2024

Natural Product Research

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The main goal of this study was to investigate the phytochemical and antioxidant potential of different extracts of propolis by conventional spectrophotometric methods. Additionally, profiling of the main constituents of propolis was done by GCMS analysis. The antioxidant activity was assessed by using 2,2 -diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay, total phenolic content and total flavonoid content were analyzed by Folin-Ciocalteu reagent method and aluminum chloride method respectively. The methanolic extract exhibited the highest antioxidant activities, the ethanolic extract had the highest total phenolic content and the maximum amount of flavonoid was observed in the chloroform extract. GC-MS analysis revealed the presence of 35 different chemical compounds, out of which 8 are main belonging to flavonoids, fatty acids, and phenolic compounds. Results revealed that propolis from Derra Bassi can be used as natural antioxidant and with its standardization can be used for the prevention of diseases related to free radicals.

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A comparative study of solvent effect on propolis extraction by ultrasound-assisted extraction

Kolaylı,

Birinci

2024

Turkish Journal of Analytical Chemistry

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Propolis is a natural bee product obtained from beehives as raw propolis. Propolis extracts obtained from raw propolis with different polarities solvents are used as food supplement agent. The composition of propolis extracts depends on the raw propolis species, extraction methods and extraction solvent. In this study, it is expressed how the phenolic composition of propolis extracts varies depending on the solvent polarity used. The ultrasonic-assisted maceration technique was used to extract an Anatolian raw propolis sample with five different polarity solvents, namely water, methanol, ethanol, isopropanol, and n-butanol using sequential and gradual extractions. The extraction capacity was evaluated by total phenolic substance content (TPC), total flavonoid substance content (TFC), individual phenolic compounds, and antioxidant capacity. The phenolic compositions were analyzed by High Performance Liquid Chromatography (HPLC-PDA) according to the twenty-five phenolic standards. As a result, it was determined 70% ethanolic extract was contained the highest phenolic compounds and antioxidant capacity.

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Determination of the effect of green extraction solvents on the phenolic acids and flavonoids of propolis

Cited by 3 publications

References 30 publications

Electrochemical analysis and in silico molecular docking with tropomyosin-related kinase B reveals electron shuttles-mediated neuroprotective potential of mandarin orange pu-erh tea extracts

Electrochemical analysis and in silico molecular docking with tropomyosin-related kinase B reveals electron shuttles-mediated neuroprotective potential of mandarin orange pu-erh tea extracts

Phytochemical potential and GC–MS analysis of propolis from Punjab region of India

A comparative study of solvent effect on propolis extraction by ultrasound-assisted extraction

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