CdSe fractional monolayer quantum dots (FMQDs) embedded in a ZnSe matrix were produced by atomic layer epitaxy with a nominal coverage of 0.5 monolayer. They have a thickness of a/2, where a is the strained perpendicular lattice constant of cubic CdSe. Their photoluminescence spectra at low temperature exhibit narrow and intense excitonic emission around 2.759 eV. Based on the experimental excitonic emission energy and applying the factorized-envelope approximation, we have estimated that the lateral dimensions of these FMQDs are around 4–5 nm and their density is cm−2.