Spatial simulation of land-use change scenarios in metropolitan areas is essential for analyzing both the causes and consequences of various future scenarios and is also valuable for land-use planning and management. However, current simulation models primarily focus on spatial and rarely on quantitative driving factors. This article aims to simulate future scenarios of land-use changes in the Tehran metropolitan region (TMR) by combining different models to fill this gap. Thus, in the first step, land-use changes were analyzed in the period 1985, 2000, and 2015. Then, by identifying the impact of driving factors and land-use transition potentials with Logistic regression (LR), land-use changes were allocated using the Cellular Automata (CA) method. Finally, with the validation of the model, four scenarios of the current trend(CT), socioeconomic growth(SEG), ecologicaloriented(EO), and integrated development(ID) were suggested with the combination of the System Dynamic (SD) model. The results show that the trend of land-use changes in TMR has led to the destruction of grassland, agricultural, and uncultivated lands and the continuation of this trend will increase the damage of built-up areas on valuable natural and ecological resources. In this way, proximity to roads, distance from built-up areas, and natural factors had the greatest impact on changes. Based on future scenarios in 2030, the change in the SEG-scenario shows a rapid increase in built-up areas (2858km 2) and encroachment on agricultural lands (2171km 2) . In the EO-scenario, destruction of grassland and agricultural lands and the growth of built-up areas will be limited, while CT-scenario leads to the high growth of built-up areas along with destructive impacts on natural and open spaces. In the ID-scenario, the built-up areas and grasslands will increase to 2808km 2 and 7438km 2 , respectively. Accordingly, policy-makers can use simulation of different scenarios to mitigate probable consequences of land-use changes in the metropolitan regions.