Determination of the protection period of fungicides used for control of Sclerotinia stem rot in soybean through bioassay and chromatography

Miorini, T; Raetano, Carlos Gilberto; Negrisoli, Matheus Mereb; Pérez-Hernández, Óscar

doi:10.1007/s10658-021-02212-z

Cited by 6 publications

(2 citation statements)

References 47 publications

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“…Currently, there is lack of soybean cultivars with medium to high levels of resistance to S. sclerotiorum , and crop rotation is not fully effective for the control of this pathogen ( Gracia-Garza et al, 2002 ; Ranjan et al, 2019 ). At present, the management of S. sclerotiorum in soybean strongly relies on the use of chemical fungicides, such as carbendazim, fluazinam, prochloraz, and procymidone ( Miorini et al, 2021 ). However, none of them offer complete control and several resistant strains have been reported ( Mao et al, 2020 ; Zhou et al, 2020 ).…”

Section: Introductionmentioning

confidence: 99%

Antifungal Mechanism and Efficacy of Kojic Acid for the Control of Sclerotinia sclerotiorum in Soybean

et al. 2022

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Sclerotinia stem rot, which is caused by the fungal pathogen Sclerotinia sclerotiorum, is a soybean disease that results in enormous economic losses worldwide. The control of S. sclerotiorum is a difficult task due to the pathogen’s wide host range and its persistent structures, called sclerotia. In addition, there is lack of soybean cultivars with medium to high levels of resistance to S. sclerotiorum. In this work, kojic acid (KA), a natural bioactive compound commonly used in cosmetic industry, was evaluated for the management of Sclerotinia stem rot. Interestingly, KA showed strong antifungal activity against S. sclerotiorum by inhibiting chitin and melanin syntheses and, subsequently, sclerotia formation. The antifungal activity of KA was not obviously affected by pH, but was reduced in the presence of metal ions. Treatment with KA reduced the content of virulence factor oxalic acid in S. sclerotiorum secretions. Preventive applications of 50 mM KA (7.1 mg/ml) completely inhibited S. sclerotiorum symptoms in soybean; whereas, in curative applications, the combination of KA with prochloraz and carbendazim improved the efficacy of these commercial fungicides. Taken together, the antifungal activity of KA against S. sclerotiorum was studied for the first time, revealing new insights on the potential application of KA for the control of Sclerotinia stem rot in soybean.

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Section: Introductionmentioning

confidence: 99%

Antifungal Mechanism and Efficacy of Kojic Acid for the Control of Sclerotinia sclerotiorum in Soybean

et al. 2022

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“…One year later, the same group published another notable work describing a nickel/photo-catalyzed C(sp 3 )-H arylation of dioxolane in the presence of several aryl chlorides (Scheme 58A) [268]. In this study, the authors built a library using known commercially available drugs as coupling partners, such as procymidone ( 181) (a known potent fungicide used in agriculture [269]), hexythiazox (183) (a known pesticide used in agriculture [270]) and zomepirac (187) (withdrawn anti-inflammatory drug [271]), from which the arylated products were obtained in moderate to good yields (Scheme 58B).…”

Section: Nickel-catalyzed C-h Activationmentioning

confidence: 99%

On the application of 3d metals for C–H activation toward bioactive compounds: The key step for the synthesis of silver bullets

Carvalho¹,

Miranda²,

Nunes³

et al. 2021

Beilstein J. Org. Chem.

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Several valuable biologically active molecules can be obtained through C–H activation processes. However, the use of expensive and not readily accessible catalysts complicates the process of pharmacological application of these compounds. A plausible way to overcome this issue is developing and using cheaper, more accessible, and equally effective catalysts. First-row transition (3d) metals have shown to be important catalysts in this matter. This review summarizes the use of 3d metal catalysts in C–H activation processes to obtain potentially (or proved) biologically active compounds.

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Novel and portable test strip platform for rapid and sensitive on-site detection of procymidone pesticide

Xu,

Zhang,

Zhang

et al. 2023

Microchim Acta

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Determination of the protection period of fungicides used for control of Sclerotinia stem rot in soybean through bioassay and chromatography

Cited by 6 publications

References 47 publications

Antifungal Mechanism and Efficacy of Kojic Acid for the Control of Sclerotinia sclerotiorum in Soybean

Antifungal Mechanism and Efficacy of Kojic Acid for the Control of Sclerotinia sclerotiorum in Soybean

On the application of 3d metals for C–H activation toward bioactive compounds: The key step for the synthesis of silver bullets

Novel and portable test strip platform for rapid and sensitive on-site detection of procymidone pesticide

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