Reduction of the primary energy consumption is a crucial challenge for the building sector due to economic and environmental issues. Substantial savings could be achieved within the household. In this paper, we investigate the energy performance of a single-family house located in the temperate climate. The assessment is based on the comprehensive thermal diagnostic of the building performed on-site and via computational analyses. The on-site measurements included diagnostics of the building envelope, heat source, heating and domestic hot water system, ventilation system, and indoor environmental quality. Analyses confirmed that the studied building, which was built in 2008, meets the legislation requirements for the primary energy usage at that time and nowadays. However, results show discrepancies between energy performance obtained through on-site measurements and computational methods following regulations. Partially, discrepancies are a result of differences on normative values and how the building is operated in practice. It is also showed how important the role in the assessment of energy consumption through measurements is played by the measurement period.