2020
DOI: 10.1021/acs.chemrestox.9b00410
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Determination of Thermal Decomposition Products Generated from E-Cigarettes

Abstract: An electronic cigarette (e-cigarette) is a product used to smoke aerosol by heating a solution of “e-liquid” that consists of propylene glycol (PG) and glycerol (GLY) containing nicotine and flavors. In this study, thermal decomposition products generated from three brands of e-cigarettes were determined at various electric power levels. When using neat PG or GLY instead of e-liquid, propylene oxide was detected only in the gas phase from PG and not detected from GLY. In contrast, glycidol was detected only fr… Show more

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Cited by 62 publications
(92 citation statements)
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“…The formaldehyde levels observed in this study were within interquartile ranges of literature values [4,13,15,[45][46][47]], but we observed wide varieties in reported formaldehyde levels. The reported e-vapor formaldehyde levels have been shown to range from 0.01 µg/puff to 342.2 µg/puff for top coil device and range from 0.02 µg/puff to 220.0 µg/puff for bottom coil e-cigarettes [4,[13][14][15]19,22,[45][46][47][48][49]. The wide range of e-cigarette carbonyl emission levels reported literatures might be a factor of the coil settings [13].…”
Section: Discussionsupporting
confidence: 80%
See 1 more Smart Citation
“…The formaldehyde levels observed in this study were within interquartile ranges of literature values [4,13,15,[45][46][47]], but we observed wide varieties in reported formaldehyde levels. The reported e-vapor formaldehyde levels have been shown to range from 0.01 µg/puff to 342.2 µg/puff for top coil device and range from 0.02 µg/puff to 220.0 µg/puff for bottom coil e-cigarettes [4,[13][14][15]19,22,[45][46][47][48][49]. The wide range of e-cigarette carbonyl emission levels reported literatures might be a factor of the coil settings [13].…”
Section: Discussionsupporting
confidence: 80%
“…Formaldehyde levels (log-scale) from e-cigarettes with different coil structure (top-and bottom coil) and power outputs (low and high levels determined by lower and higher power outputs [5 watts for top coil and 18 watts for bottom coil] used in the literatures). Red dots indicate our results, and black dots are the results obtained from literatures[4,[13][14][15]19,22,[45][46][47][48][49]. Formaldehyde levels in cigarette smoke from literatures[50][51][52] are shown for comparison purpose.…”
mentioning
confidence: 99%
“…The nAChR deletion may promote inflammation independent of nicotine exposure in the lungs. The chemicals derived from e-cig aerosols containing PG, such as formaldehyde, acetaldehyde, and methylglyoxal, in nicotine-free aerosol [32] may result in increased inflammation. As reported previously, both e-cig with or without nicotine caused infiltration of inflammatory cells and pro-inflammatory mediators that are key players for causing lung inflammatory response [8,11,30].…”
Section: Discussionmentioning
confidence: 99%
“…The nAChR deletion may promote inflammation independent of nicotine exposure in the lungs. The chemical derived from e-cig aerosols containing PG, such as formaldehyde, acetaldehyde, and methylglyoxal, in nicotine-free aerosol [32], may result in increased inflammation. As reported previously, both e-cig with or without nicotine caused infiltration of inflammatory cells and pro-inflammatory mediators that are key players for causing lung inflammatory response [8,11,30].…”
Section: Discussionmentioning
confidence: 99%