Straw mulching (SM) plays an important role in promoting the grain yield (GY) of maize under no-tillage conditions. However, there is still a lack of deep understanding on the interactive impact of SM and weather conditions on agronomic traits and the contributions to GY. This study selected a cornfield in the North China Plain as the research object and set up a straw management experiment, including SM and no straw mulching (NSM). The GY and agronomic traits of maize from 2018 to 2020 were monitored, and the relationship of agronomic traits with GY and the weather conditions were analyzed. The results show that SM promoted maize GY by 20.44%. Straw mulching increased the plant height, ear diameter, and ear height by 8.43%, 1.99%, and 12.65%, respectively. A correlation analysis showed that the ear length and ear height were the main factors affecting maize yield. Ear length was significantly correlated with kernel numbers per ear in SM. Growing degree days, hot dry wind, and air temperature significantly affected kernel numbers per ear and plant growth. This study highlights the contributions of agronomic factors to maize GY under SM and variable weather conditions and is helpful to improve cropland management.